Tuberc Respir Dis.
2002 Mar;52(3):278-282.
Idiopathic Fibrosing Mediastinitis Causing Extensive Fibrotic Veno-occlusion with Minimal Mediastinal Involvement
- Affiliations
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- 1Department of Internal Medicine, College of Medicine, Korea University, Seoul, Korea. jaejshim@kumc.or.kr
- 2Department of Pathology, College of Medicine, Korea University, Seoul, Korea.
- 3Department of Internal Medicine, College of Medicine, Wonkwang University, Iksan, Korea.
Abstract
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A 68-year-old woman was admitted after suffering facial edema with neck vein engorgement ofr approximately 2 months. A chest X-ray showed a mild widening of the superior mediastinum and a luminal obliteration of the super ior vena cava (SVC) was noted on a computed tomograph. Venography showed that both subclavian veins were obstructed at the level of the poxima clavicle with a nonvisualization of the SVC. The SVC, both the innominate and the left inthrnal jugular veins were completely obstructed with extensive cord-like fibrotix changes despite the obsence of mediastinal involvement. The microscopic features showed a chronic granulomatous inflammation with a fibrosis minimally invading the mediastinal fat, which is cosistent with fibrosing mediastinitis.