Tuberc Respir Dis.  2002 Mar;52(3):278-282.

Idiopathic Fibrosing Mediastinitis Causing Extensive Fibrotic Veno-occlusion with Minimal Mediastinal Involvement

Affiliations
  • 1Department of Internal Medicine, College of Medicine, Korea University, Seoul, Korea. jaejshim@kumc.or.kr
  • 2Department of Pathology, College of Medicine, Korea University, Seoul, Korea.
  • 3Department of Internal Medicine, College of Medicine, Wonkwang University, Iksan, Korea.

Abstract

A 68-year-old woman was admitted after suffering facial edema with neck vein engorgement ofr approximately 2 months. A chest X-ray showed a mild widening of the superior mediastinum and a luminal obliteration of the super ior vena cava (SVC) was noted on a computed tomograph. Venography showed that both subclavian veins were obstructed at the level of the poxima clavicle with a nonvisualization of the SVC. The SVC, both the innominate and the left inthrnal jugular veins were completely obstructed with extensive cord-like fibrotix changes despite the obsence of mediastinal involvement. The microscopic features showed a chronic granulomatous inflammation with a fibrosis minimally invading the mediastinal fat, which is cosistent with fibrosing mediastinitis.

Keyword

Fibrosing mediastinitis; Superior vena cave syndrome

MeSH Terms

Aged
Clavicle
Edema
Female
Fibrosis
Humans
Inflammation
Jugular Veins
Mediastinitis*
Mediastinum
Neck
Phenobarbital
Phlebography
Subclavian Vein
Thorax
Veins
Phenobarbital
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