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Chronic Reserpine Administration for Depression Modeling in Zebrafish

Kim S, Han C, Ko YH, Kim YK, Yoon HK, Lee J, Kim S, Lee C, Shin C

Objectives This study aims to develop valid experimental models for depression through chronic reserpine exposure to zebrafish (Danio rerio). Methods The effect of chronic reserpine on zebrafish behavior in the novel tank was...
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Plasminogen Activator Inhibitor-1: Potential Inflammatory Marker in Late-life Depression

Lee SH, Shin C, Ko YH, Lee MS, Park MH, Pae CU, Yoon HK, Han C

Objective: Although several previous studies have examined the association between late-life depression and blood adipokine levels, a marker of chronic inflammation, no studies have comprehensively considered the effects of metabolic...
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Indications for Lung Transplantation and Patient Selection

Son J, Shin C

Globally, thousands of patients undergo lung transplantation owing to end-stage lung disease each year. As lung transplantation evolves, recommendations and indications are constantly being updated. In 2021, the International Society...
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Cytomegalovirus-Specific Immunotherapy for Glioblastoma Treatments

Ahn J, Shin C, Kim YS, Park JS, Jeun SS, Ahn S

Over the last two decades, numerous studies have investigated the presence of human cytomegalovirus (CMV) within glioblastoma or gliomas; however, the results are severely conflicting. While a few researchers have...
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Effects of exercise on AKT/PGC1-α/FOXO3a pathway and muscle atrophy in cisplatin-administered rat skeletal muscle

Bae JH, Seo DY, Lee SH, Shin C, Jamrasi P, Han J, Song W

Cisplatin has been reported to cause side effects such as muscle wasting in humans and rodents. The physiological mechanisms involved in preventing muscle wasting, such as the regulation of AKT,...
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Insomnia in Emotional Labor: Its Role in Autonomic Nervous System Regulation

Chae B, Kang J, Shin C, Ko YH, Yoon HK

Objective The relation between female emotional laborers’ sleep quality and autonomic nervous system activity was investigated. Methods Thirty-three subjects’ heart rate variability (HRV) data and results of self-reported scale on sleep,...
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Investigation of Nocturnal Hypokinesia and Health-Related Quality of Life in Parkinsonian Patients with the Korean Version of the Nocturnal Hypokinesia Questionnaire

Choi JH, Lee JY, Shin C, Yoo D, Im JH, Woo KA, Kim HJ, Ahn TB, Kim JM, Jeon B

Objective To assess nocturnal hypokinesia using the Korean version of the Nocturnal Hypokinesia Questionnaire (NHQ-K) in Parkinson’s disease (PD) patients across disease stages. Methods We developed the NHQ-K and performed questionnaire-based...
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Changes in Brain Electrical Activity According to Post-traumatic Stress Symptoms in Survivors of the Sewol Ferry Disaster: A 1-year Longitudinal Study

Jin S, Shin C, Han C, Kim YK, Lee J, Jeon SW, Lee SH, Ko YH

Objective: The pathology of post-traumatic stress disorder (PTSD) is associated with changes in brain structure and function, especially in the amygdala, medial prefrontal cortex, hippocampus, and insula. Survivors of tragic...
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Safety and Effectiveness of Cytomegalovirus Specific Antigen Induced Interferon-Gamma ELISPOT/ELISA: A Systematic Review

Choi W, Hahn J, Lee W, Shin C

Background: This study evaluated the safety and effectiveness of the cytomegalovirus (CMV) Specific Antigen Induced Interferon-Gamma ELISPOT (enzyme-linked immunosorbent spot)/ELISA (enzyme-linked immunosorbent assay) procedure in predicting the risk of CMV...
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Additional Reduction of Residual Symptoms with Aripiprazole Augmentation in the Patients with Partially Remitted Major Depressive Disorder

Shin C, Pae CU, Kwak KP, Jeon SW, Jeong HG, Kim JW, Lee YJ, Patkar AA, Han C

Objective: Many patients with major depressive disorder (MDD) suffer from residual symptoms without achieving remission. However, pharmacologic options for residual symptoms of MDD have been limited. This study aimed to...
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The Behavioral Effects of Combination Therapy of Memantine and Acetylcholinesterase Inhibitors Compared with Acetylcholinesterase Inhibitors Alone in Patients with Moderate Alzheimer’s Dementia: A Double-Blind Randomized Placebo-Controlled Trial

Youn H, Lee KJ, Kim SG, Cho SJ, Kim WJ, Lee WJ, Hwang JY, Han C, Shin C, Jung Hy

Objective This study aimed to investigate treatment effects of combination therapy of memantine and acetylcholinesterase inhibitors (AchEIs) compared with AchEIs alone on behavioral and psychological symptoms of dementia (BPSD) in...
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Standardization of the Korean Version of the Patient Health Questionnaire-4 (PHQ-4)

Kim HW, Shin C, Lee SH, Han C

Objective: The Patient Health Questionnaire-4 (PHQ-4) has been used for screening owing to ease of use and brevity. In this study, we developed the Korean version of the PHQ-4 and tested...
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A Treatment of Recurrent Clear Cell Hidradenoma on the Neck: A Case Report

Kim SJ, Yang H, Shin C, Oh SH

Clear cell hidradenoma is a skin adnexal tumor originating from eccrine glands. The risk of local recurrence after surgical resection exceeds 50%, and 6-19% of cases are malignant. The rarity...
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Cadaveric study of deep temporal fascia for autologous rhinoplasty grafts: Dimensions of the temporal compartment in Asians

Chi D, Kim JH, Kim TK, Jeong JY, Shin C, Kim S, Oh SH

Background Due to the anatomical complexity of the deep temporal fascia (DTF), practical guidelines for its safe harvest are lacking. However, since the upper temporal compartment (UTC) contains no vital...
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Efficacy of Buspirone Augmentation of Escitalopram in Patients with Major Depressive Disorder with and without Atypical Features: A Randomized, 8 Week, Multicenter, Open-Label Clinical Trial

Shin C, Ko YH, Shim SH, Kim JS, Na KS, Hahn SW, Lee SH

Objective This study investigated the treatment response and cognitive enhancement effects of buspirone augmentation of escitalopram in patients with major depressive disorder (MDD), according to atypical feature subtypes of MDD. Methods...
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Alternating Hemiplegia of Childhood in Korea: a Case Report

Shin C, Yoo D, Kim HJ, Jeon B

Alternating hemiplegia of childhood (AHC) is a rare neurodevelopmental disorder characterized by recurrent paroxysmal hemiplegic attacks that affect one or the other side of the body. Up to 74% of...
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Ketamine in Major Depressive Disorder: Mechanisms and Future Perspectives

Shin C, Kim YK

Major depressive disorder (MDD) is a serious psychiatric illness that causes functional impairment in many people. While monoaminergic antidepressants have been used to effectively treat MDD, these antidepressants have limitations...
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Experiences of Latent Tuberculosis Infection Treatment for the North Korean Refugees

Kim BK, Kim HJ, Kim HJ, Cha JH, Lee JB, Jeon J, Kim CY, Kim Y, Kim JH, Shin C, Lee SH

BACKGROUND: Tuberculosis (TB) is increasing in immigrants. We aimed to investigate the current status of latent tuberculosis infection (LTBI) treatment for North Korean Refugees (NKR) compared to South Koreans Contacts...
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Comparison of the Usefulness of the PHQ-8 and PHQ-9 for Screening for Major Depressive Disorder: Analysis of Psychiatric Outpatient Data

Shin C, Lee SH, Han KM, Yoon HK, Han C

OBJECTIVE: This study aimed to demonstrate that the Patient Health Questionnaire (PHQ)-8 is not less useful than the PHQ-9 as a screening test for major depressive disorder (MDD). METHODS: We performed...
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Comorbid Zolpidem Dependence and Over-the-Counter Compound Analgesic Abuse

Kim H, Shin C, Ko YH, Han C

Zolpidem is a commonly prescribed hypnotic used to treat insomnia. However, its potential for abuse and dependence has recently become controversial. Although over-the-counter (OTC) medications are widely used, their abuse...
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