Prog Med Phys.  2018 Sep;29(3):81-91. 10.14316/pmp.2018.29.3.81.

Effect of Particulate Matter on Human Health, Prevention, and Imaging Using PET or SPECT

• Zaheer J
• Jeon J
• Lee SB
• Kim JS

• KMID: 2421704
• DOI: http://doi.org/10.14316/pmp.2018.29.3.81

Abstract

Particulate matter (PM) in dust causes serious pathological conditions, and it has been considered a critical health issue for many years. Respiratory disorders such as bronchitis, asthma, and chronic inflammation, are the most common illnesses due to PM that appears as dust. There is evidence that cardiovascular and neurological abnormalities are caused by PM. Although an extensive amount of work has been conducted on this topic, including studies on the nature of the particles, particle size measurements, particle distribution upon inhalation, the health effects of fine particles, disease prevention, diagnosis, and treatment, to this date, there is still a considerable lack of knowledge in these areas. Therefore, the identification of the key components that cause diseases owing to PM, and the specific diagnoses of the diseases, is important. This review will explore the current literature on the origin and nature of PM and their effects on human health. In addition, it will also highlight the approaches that have been adopted in order to diagnose the effects of PM using positron emission tomography (PET) or single-photon emission computerized tomography (SPECT).

Keyword

Particulate matter; PET; SPECT; Imaging

MeSH Terms

Asthma
Bronchitis
Diagnosis
Dust
Humans*
Inflammation
Inhalation
Particle Size
Particulate Matter*
Positron-Emission Tomography
Tomography, Emission-Computed, Single-Photon*
Dust
Particulate Matter

Figure

• 

  Fig. 1 Diagrammatic representation of inhaled particulate matter (PM) of variable sizes. PM-linked respiratory, cardiovascular, and neurological disorders and imaging of effect of PM on human health using PET or SPECT.

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