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Does the Incremental Value of  123 I-Metaiodobenzylguanidine SPECT/ CT over Planar Imaging Justify the Increase in Radiation Exposure?

Ben-Sellem D, Ben-Rejeb N

Purpose Planar scintigraphy with 123 I-radiolabeled metaiodobenzylguanidine (123 I-mIBG) is an important imaging modality to evaluate neuroblastoma. In recent years, Single Photon Emission Computed Tomography combined with Computed Tomography (SPECT/CT)...
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Nuclear Imaging for Cardiac Amyloidosis: Bone Scan, SPECT/CT, and Amyloid-Targeting PET

Paeng JC, Choi JY

Cardiac amyloidosis (CA) is a type of systemic amyloidosis, in which abnormal amyloid fibril is deposited in extracellular space of myocardium. Most common subtypes of CA are amyloidosis of immunoglobulin...
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Usefulness of  99m Tc-SESTAMIBI Scintigraphy in Persistent Hyperparathyroidism after Kidney Transplant

Shin M, Choi JY, Kim SW, Kim JH, Cho YS

Purpose 99m Tc-labeled sestamibi scintigraphy combined with single-photon emission computed tomography (SPECT) has a high positive predictive value for localizing hyperfunctioning parathyroid lesions in primary hyperparathyroidism (pHPT) but relatively low...
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KSNM60 in Clinical Nuclear Oncology

Moon S, Cho Y, Choi J

Since the foundation of the Korean Society of Nuclear Medicine in 1961, clinical nuclear oncology has been a major part of clinical nuclear medicine in Korea. There are several important...
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Simulating dose reduction for myocardial perfusion SPECT using a Poisson resampling method

Kim IH, Lee S, An YS, Choi SY, Yoon JK

Purpose The purpose of this study was to determine the lowest Tl-201 dose that does not reduce the image quality of myocardial perfusion SPECT (MPS) by Poisson resampling simulation. Methods One...
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Physiological Uptake of Radioactive Iodine Around an ArtificialEyeball Observed with Single-Photon Emission ComputedTomography/Computed Tomography After RadioactiveIodine Treatment

Lee JY, Song HS, Kang M

Radioactive iodine treatment is useful for ablating remnant thyroid tissue and metastasis ofwell-differentiated thyroid cancer withlong-lasting effects. A scintigraphy after radioactive iodine treatment is a major imaging modality for detecting...
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Radioisotope-ADME studies of Trastuzumab-monomethyl auristatin F in tumor bearing mice and healthy marmosets

Lee HW, Jeong YH, Hwang JA, Lee JJ, Yu AR, Kang JA, Raza MA, Park SH, Park YH, Kim DH

Radioisotope ADME (RI-ADME) studies are enabling visualization of the biodistribution in molecular imaging. We applied RI-ADME to investigate the tumor targeting capacity and biodistribution of trastuzumab-monomethyl auristatin F (LCB14-0110) in...
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Computed Tomography (CT) Protocols Associated with Cardiac and Bone Single-Photon Emission Computed Tomography/CT (SPECT/CT) in Korea

Lee EJ, Kim JY, Park JM, Song BI, Choi H, Shim Hk, Park HL, Lee HY, Lee KJ, Yoon JK, Seo S, Kim SM, Park SB, Cho YS, Kim SH

Purpose: Single-photon emission computed tomography/computed tomography (SPECT/CT) is an advanced hybrid nuclear medicine technology that generates both functional and anatomical images in a single study. As utilization of SPECT/CT in...
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Basal and Acetazolamide Brain Perfusion SPECT in Internal Carotid Artery Stenosis

Wong TH, Shagera QA, Ryoo HG, Ha S, Lee DS

Internal carotid artery (ICA) stenosis including Moyamoya disease needs revascularization when hemodynamic insufficiency is validated. Vascular reserve impairment was the key to find the indication for endarterectomy/bypass surgery in the...
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Bone SPECT/CT of the Foot and Ankle: Potential Clinical Application for Chronic Foot Pain

Yoo IR

Diseases of the foot and ankle are common but relatively difficult to diagnose because of the complexity of the anatomy and the frequent occurrence of multiple diseases at the same...
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Use of Molecular Imaging in Clinical Drug Development: a Systematic Review

Son H, Jang K, Lee H, Kim SE, Kang KW, Lee H

BACKGROUND: Molecular imaging such as positron emission tomography (PET) and single-photon emission computed tomography (SPECT) can provide the crucial pharmacokinetic-pharmacodynamic information of a drug non-invasively at an early stage of...
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Development of a Novel Imaging Agent for Determining Albumin Uptake in Solid Tumors

Daum S, Magnusson , Pes L, Garcia Fernandez J, Chercheja , Medda F, Nollmann F, Koester SD, Perez Galan P, Warnecke A, Abu Ajaj K, Kratz F

PURPOSE: The purpose of this study was to investigate the albumin-binding compound 111In-C4-DTPA as an imaging agent for the detection of endogenous albumin accumulation in tumors. METHODS: 111In-C4-DTPA was injected in...
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Quantitative Imaging of Alpha-Emitting Therapeutic Radiopharmaceuticals

Seo Y

Targeted alpha therapy (TAT) is an active area of drug development as a highly specific and highly potent therapeutic modality that can be applied to many types of late-stage cancers....
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The Lymphatic Drainage Pattern of Internal Mammary Sentinel Lymph Node Identified by Small Particle Radiotracer ((99m)Tc-Dextran 40) in Breast

Cao XS, Yang GR, Cong BB, Qiu PF, Wang YS

PURPOSE: The purpose of this study was to detect the lymphatic drainage pattern of internal mammary area and verify the concept of internal mammary sentinel lymph node (IM-SLN) in breast. MATERIALS...
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Assessment of Left Ventricular Ejection Fraction by Thallium-201 Myocardial SPECT-CT in Patients with Angina Pectoris: Comparison with 2D Echocardiography

Kim JY, Park HC, Kim SJ, Chang HS, Choi HJ, Kim YH

PURPOSE: Left ventricular (LV) ejection fraction (EF) is an important parameter for assessing cardiac systolic function and predicting prognosis in patients with cardiovascular disease. The aim of this study was...
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Analysis of Mechanical Loading after Anatomic Anterior Cruciate Ligament Reconstruction Using Combined Single-Photon Emission Computerized Tomography and Conventional Computerized Tomography

Kim BK, Kim TW, Hwang CH, Park HK, Hwang KH, Sim JA, Lee YS, Lee BK

PURPOSE: This study was to evaluate changes of the mechanical loading pattern after anatomic anterior cruciate ligament (ACL) reconstruction by analyzing uptake patterns using combined single-photon emission computerized tomography and...
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Comparative Cardiac Phantom Study Using Tc-99m/I-123 and Tl-201/I-123 Tracers with Cadmium-Zinc-Telluride Detector-Based Single-Photon Emission Computed Tomography

Niimi T, Nanasato M, Sugimoto M, Maeda H

OBJECTIVE: A recently introduced single-photon emission computed tomography (SPECT), based on cadmium-zinc-telluride (CZT) detectors (D-SPECT), supports high energy resolution for cardiac imaging. Importantly, the high energy resolution may allow simultaneous...
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Dawn of Theranostics in Myanmar (Dream, Reality, and Constraint)

Myint K, Thein TM, Phyu TK, Maung W

Prostate cancer is third common malignancy in men of old age (average 65 years) in Myanmar. Currently, serum PSA and bone scan are the markers of choice. Because of the...
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Effect of ME Collimator Characteristic, Energy Window Width, and Reconstruction Algorithm Selection on Imaging Performance of Yttrium-90: Simulation Study

Taherparvar P, Shahmari N

PURPOSE: The treatment efficiency of ⁹⁰Y and providing reliable estimates of activity are evaluated by SPECT imaging of bremsstrahlung radiation released during beta therapy. In this technique, the resulting spectrum...
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Comparative Analysis of Lung Perfusion Scan and SPECT/CT for the Evaluation of Functional Lung Capacity

Suh HY, Park S, Ryoo HG, Kim JY, Kim TS, Lee JM, Kim MS, Yang HC, Kim SK

PURPOSE: This study aimed to compare lung perfusion scan with single photon emission computed tomography/computed tomography (SPECT/CT) for the evaluation of lung function and to elucidate the most appropriate modality...
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