Psychiatry Investig.
2018 Aug;15(8):767-774. 10.30773/pi.2018.06.02.
Overview of the Korean Longitudinal Study on Cognitive Aging and Dementia
- Affiliations
-
- 1Department of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Republic of Korea. kwkimmd@snu.ac.kr
- 2Department of Psychiatry, Yonsei University Wonju Severance Christian Hospital, Wonju, Republic of Korea.
- 3Department of Psychiatry, Dongguk University Gyeongju Hospital, Gyeongju, Republic of Korea.
- 4Department of Psychiatry, National Center for Mental Health, Seoul, Republic of Korea.
- 5Department of Psychiatry, Gyeongsang National University School of Medicine, Jinju, Republic of Korea.
- 6Department of Neuropsychiatry, Soonchunhyang University Bucheon Hospital, Bucheon, Republic of Korea.
- 7Department of Psychiatry, School of Medicine, Chungnam National University, Daejeon, Republic of Korea.
- 8Department of Psychiatry, School of Medicine, Konkuk University, Konkuk University Chungju Hospital, Chungju, Republic of Korea.
- 9Department of Neuropsychiatry, Jeju National University Hospital, Jeju, Republic of Korea.
- 10Department of Neuropsychiatry, Changwon Gyeongsang National University Hospital, Changwon, Republic of Korea.
- 11Department of Psychiatry, School of Medicine, Konkuk University, Konkuk University Medical Center, Seoul, Republic of Korea.
- 12Department of Neuropsychiatry, Kyunggi Provincial Hospital for the Elderly, Yongin, Republic of Korea.
- 13Department of Psychiatry, Bongseng Memorial Hospital, Busan, Republic of Korea.
- 14Department of Neuropsychiatry, Seoul National University Hospital, Seoul, Republic of Korea.
- 15Department of Psychiatry, Seoul National University College of Medicine, Seoul, Republic of Korea.
- 16Department of Neuropsychiatry, Inje University Sanggye Paik Hospital, Seoul, Republic of Korea.
- 17Department of Psychiatry, Dankook University Hospital, Cheonan, Republic of Korea.
- 18Department of Psychiatry, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Republic of Korea.
- 19Department of Psychiatry, Kangwon National University School of Medicine, Chuncheon, Republic of Korea.
- 20Department of Brain and Cognitive Science, Seoul National University College of Natural Sciences, Seoul, Republic of Korea.
- KMID: 2419365
- DOI: http://doi.org/10.30773/pi.2018.06.02
Abstract
OBJECTIVE
Due to an unprecedented rate of population aging, South Korea is facing a dementia epidemic. For this reason, the Korean Longitudinal Study on Cognitive Aging and Dementia (KLOSCAD) was launched in 2009 with support from the Korean Health Industry Development Institute to investigate the epidemiology, biopsychosocial risk factors, and outcomes of dementia and dementia-related conditions.
METHODS
The KLOSCAD is the first nationwide multi-center population-based prospective cohort study. In October 2010, 12,694 individuals were randomly sampled from residents aged 60 years or older who lived in 13 districts across South Korea. In the baseline assessment, which was conducted from November 2010 through October 2012, 6,818 (53.7%) individuals participated. Follow-up assessments have been conducted every two years, with the first follow-up assessment conducted between November 2012 and October 2014, and the second between November 2014 and October 2016. The third is now in progress, and will span from November 2016 to October 2018. Diagnosis of cognitive disorders, neuropsychological battery, behavioral and psychological symptoms of dementia, activities of daily living, physical and neurologic examination and laboratory tests, life styles, quality of life, and identification of death were evaluated in each assessment.
RESULTS
The cumulative drop-out rate at the second follow-up assessment was 38.7%. Dementia and mild cognitive impairment were 5.0% and 27.0%, respectively.
CONCLUSION
The KLOSCAD may provide strong scientific evidence for advancing the fight against dementia both in Korea and globally.
