Pediatr Gastroenterol Hepatol Nutr.  2018 Jul;21(3):163-169. 10.5223/pghn.2018.21.3.163.

Gastritis Associated with Initially Pediatric Crohn's Disease and Ulcerative Colitis

• Basturk A
• Artan R
• Yılmaz A
• Gelen MT

• KMID: 2415593
• DOI: http://doi.org/10.5223/pghn.2018.21.3.163

Abstract

PURPOSE
The aim of this study is to determine the involvement of the upper gastrointestinal system (GIS) in patients diagnosed with Crohn's disease (CD), ulcerative colitis (UC), and non-inflammatory bowel disease (IBD) and to compare their differences.
METHODS
This study included patients aged between 2 and 18 years who underwent colonoscopy and esophagogastroduodenoscopy (EGD) for the first time due to the prediagnosis of IBD. In EGD, samples were taken from duodenum, antrum, corpus, and esophagus; and gastritis, duodenitis, and esophagitis were identified through histopathologic examination. The data gathered the ends of the research were compared between IBD with non-IBD groups and between CD-UC with non-IBD groups, and the presence of significant differences between groups were determined.
RESULTS
In our study, 16 patients were diagnosed with CD, 13 with UC, 3 with undeterminate colitis, and 13 with non-IBD. In the histopathological examination of the groups, GIS involvement was found in 94.1% of patients diagnosed with IBD and in 38.5% of non-IBD patients. Moreover, the difference was found to be statistically significant (p=0.032). No significant difference was found between the CD and UC groups. Gastritis was mostly observed in 93.8% of CD-diagnosed patients, 76.8% of UC-diagnosed patients, 81.2% of IBD-diagnosed patients, and 38.5% of non-IBD-diagnosed patients. On the other hand, significant differences were found between CD and non-IBD groups (p=0.03), UC and non-IBD groups (p=0.047), and IBD and non-IBD groups (p=0.03).
CONCLUSION
The results of the study show that gastritis was highly observed in UC- and CD-diagnosed patients than in non-IBD-diagnosed patients.

Keyword

Crohn's disease; Child; Gastritis; Ulcerative colitis

MeSH Terms

Child
Colitis
Colitis, Ulcerative*
Colonoscopy
Crohn Disease*
Duodenitis
Duodenum
Endoscopy, Digestive System
Esophagitis
Esophagus
Gastritis*
Hand
Humans
Ulcer*

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