J Vet Sci.  2017 Mar;18(1):115-118. 10.4142/jvs.2017.18.1.115.

Recurrence after exenteration for canine orbital malignant schwannoma

• Kang S
• Yang J
• Lee Y
• Pyo H
• Kim J
• Seo K

• KMID: 2412597
• DOI: http://doi.org/10.4142/jvs.2017.18.1.115

Abstract

A 14-year-old Maltese dog presented with progressive exophthalmos and external deviation of the right eye. Ultrasonography revealed the presence of a retrobulbar mass and fine-needle aspiration cytology was performed, which detected a malignant mass. There was no evidence of metastasis on thoracic and abdominal radiography. Computed tomography showed no invasion into the bony orbit and no metastasis to the lung or lymph nodes. Exenteration was performed to remove the mass completely. Malignant peripheral nerve sheath tumor was confirmed by histopathological examination.

Keyword

dogs; neoplasms; neurilemmoma; orbit

MeSH Terms

Animals
Dog Diseases/diagnostic imaging/etiology/*surgery
Dogs
Exophthalmos/etiology/surgery/veterinary
Male
*Neoplasm Recurrence, Local
Neurilemmoma/diagnostic imaging/etiology/surgery/*veterinary
Orbital Neoplasms/diagnostic imaging/etiology/surgery/*veterinary
Prognosis
Tomography, X-Ray Computed/veterinary

Figure

• 

  Fig. 1 Computed tomography (CT) images. (A and B) Contrast-enhanced CT images showing an irregular hypodense mass with surrounding contrast-enhancing tissue. (C) A three-dimensional CT reconstruction image. *Mass, †Eye.

• 

  Fig. 2 Tumor cells were arranged in an elongated shape or a polyhedral pattern (A) with high mitotic figures (arrows) (B), and demonstrated positive reactions for neuron-specific enolase (C). H&E stain (A and B) and immunohistochemistry (C). Scale bars = 50 µm (A), 20 µm (B and C).

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