J Korean Ophthalmol Soc.  1996 Sep;37(9):1555-1560.

A Case of the Orbital Aspergillosis

Affiliations
  • 1Department of Ophthalmology, Presbyterian Medical Cender, Chonju, Korea.

Abstract

Aspergillus is also a saprophytic, ubiquitous fungus that is normally not pathogenic in humans. When it does appear as a source of infection, the rhinoorbital route of entry seemes to parallel that of the Phacomycetes. We experienced a case of orbital aspergillosis in healthy woman. There was no intracraneal extension. In spite of local infiltration of amphotericin B solution through maxillary sinus and aggressive systemic amphotericin B therapy, ocular symptom and sign was not improved. So we performed orbital exenteration and adjunctive amphotericin B and itraconazol systemically. Six months later the patient is alive without recurrence. We reviewed the available literatures regarding this uncommon disease.

Keyword

Aspergillus; Amphotericin B; Orbital aspergillosis; Orbital exenteration

MeSH Terms

Amphotericin B
Aspergillosis*
Aspergillus
Female
Fungi
Humans
Maxillary Sinus
Orbit*
Recurrence
Amphotericin B
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