Korean J Med.  2017 Jun;92(3):316-320. 10.3904/kjm.2017.92.3.316.

Systemic Sclerosis Associated with Non-small Cell Lung Cancer and Papillary Thyroid Cancer: Case Report and Literature Review

• Kim HJ
• Kim JJ
• Park HJ
• Kim YT

• KMID: 2410196
• DOI: http://doi.org/10.3904/kjm.2017.92.3.316

Abstract

We report the case of a 52-year-old patient with rheumatic vascular disease (systemic sclerosis), non-small cell lung cancer, and papillary thyroid cancer. Malignant tumors have been described in 3-11% of systemic sclerosis cases. Several studies have demonstrated an increased frequency of cancer, especially lung and breast cancer, in patients with systemic sclerosis, but the association of systemic sclerosis with malignancy is controversial. To our knowledge, however, no case of both lung and thyroid cancer associated with systemic sclerosis has been reported. We present a rare case of double primary cancer in systemic sclerosis, with a literature review.

Keyword

Scleroderma, Systemic; Carcinoma, Non-Small-Cell Lung; Thyroid cancer, Papillary; Paraneoplastic syndromes

MeSH Terms

Breast Neoplasms
Carcinoma, Non-Small-Cell Lung*
Humans
Lung
Middle Aged
Paraneoplastic Syndromes
Scleroderma, Systemic*
Thyroid Gland*
Thyroid Neoplasms*
Vascular Diseases