J Korean Rheum Assoc.  2006 Dec;13(4):343-347.

A Case of Systemic Sclerosis Combined with Ovarian Cancer

• Choi HS
• Kim GT
• Kuon HJ
• Hwang JH
• Ryu HS
• Lee JN
• Jang SM

Abstract

We report a 54-year old female who had mild dyspnea, coughing, abdominal distension, tightening and thickening of the skin, and Raynaud's phenomenon. Clinical manifestations, laboratory and radiologic examinations were compatible with systemic sclerosis. She was also diagnosed to have ovarian cancer on histopathologic study. The possible causative relation between systemic sclerosis and malignant neoplasms is a controversial issue, but several studies have demonstrated an increased frequency of cancer in patients with systemic sclerosis, especially lung and breast cancers. Ovarian cancer was rarely reported in association with systemic sclerosis. We present this case with a review of literatures.

Keyword

Systemic sclerosis; Malignancy; Ovarian cancer

MeSH Terms

Breast
Cough
Dyspnea
Female
Humans
Lung
Middle Aged
Ovarian Neoplasms*
Scleroderma, Systemic*
Skin