Allergy Asthma Immunol Res.  2018 May;10(3):187-188. 10.4168/aair.2018.10.3.187.

The Emerging Role of TRPV1 in Airway Inflammation

• Kim JH

• KMID: 2409053
• DOI: http://doi.org/10.4168/aair.2018.10.3.187

Abstract

No abstract available.

MeSH Terms

Inflammation*

Reference

1. Grace MS, Baxter M, Dubuis E, Birrell MA, Belvisi MG. Transient receptor potential (TRP) channels in the airway: role in airway disease. Br J Pharmacol. 2014; 171:2593–2607.

2. Belvisi MG, Birrell MA. The emerging role of transient receptor potential channels in chronic lung disease. Eur Respir J. 2017; 50.

3. Hwang SW, Cho H, Kwak J, Lee SY, Kang CJ, Jung J, et al. Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances. Proc Natl Acad Sci U S A. 2000; 97:6155–6160.

4. Song WJ, Morice AH. Cough Hypersensitivity Syndrome: a few more steps forward. Allergy Asthma Immunol Res. 2017; 9:394–402.

5. Baxter M, Eltom S, Dekkak B, Yew-Booth L, Dubuis ED, Maher SA, et al. Role of transient receptor potential and pannexin channels in cigarette smoke-triggered ATP release in the lung. Thorax. 2014; 69:1080–1089.

6. McGarvey LP, Butler CA, Stokesberry S, Polley L, McQuaid S, Abdullah H, et al. Increased expression of bronchial epithelial transient receptor potential vanilloid 1 channels in patients with severe asthma. J Allergy Clin Immunol. 2014; 133:704–712.e4.

7. Cho JY, Lee HY, Hur J, Kim KH, Kang JY, Rhee CK, et al. TRPV1 blocking alleviates airway inflammation and remodeling in a chronic asthma murine model. Allergy Asthma Immunol Res. 2018; 10:216–224.

8. Kark T, Bagi Z, Lizanecz E, Pasztor ET, Erdei N, Czikora A, et al. Tissue-specific regulation of microvascular diameter: opposite functional roles of neuronal and smooth muscle located vanilloid receptor-1. Mol Pharmacol. 2008; 73:1405–1412.

9. Czikora A, Rutkai I, Pasztor ET, Szalai A, Porszasz R, Boczan J, et al. Different desensitization patterns for sensory and vascular TRPV1 populations in the rat: expression, localization and functional consequences. PLoS One. 2013; 8:e78184.

10. Devos FC, Boonen B, Alpizar YA, Maes T, Hox V, Seys S, et al. Neuro-immune interactions in chemical-induced airway hyperreactivity. Eur Respir J. 2016; 48:380–392.