Epidemiol Health.
2017;39:e2017016. 10.4178/epih.e2017016.
Cardiovascular and Metabolic Diseases Etiology Research Center (CMERC) cohort: study protocol and results of the first 3 years of enrollment
- Affiliations
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- 1Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Korea. hckim@yuhs.ac
- 2Cardiovascular and Metabolic Diseases Etiology Research Center, Yonsei University College of Medicine, Seoul, Korea.
- 3Department of Public Health, Yonsei University Graduate School, Seoul, Korea.
- 4Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Korea.
- 5Cardiovascular and Metabolic Disease Etiology Research Center, Ajou University School of Medicine, Suwon, Korea.
- 6Division of Cardiology, Severance Cardiovascular Hospital and Cardiovascular Research Institute, Yonsei University College of Medicine, Seoul, Korea.
- 7Department of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, Korea.
- 8Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.
- KMID: 2406620
- DOI: http://doi.org/10.4178/epih.e2017016
Abstract
- Although the etiologies of cardiovascular disease (CVD) are widely understood, the goal of finding a globally effective solution for preventing CVD is unrealistic. Therefore, we aimed to conduct a community-based prospective study on the prevention and management of CVD in Korean adults. This study was designed to recruit 8,000 healthy adults over the course of 5 years. The baseline assessment includes a wide range of established CVD risk factors, including demographic characteristics, medical history, health behaviors, psychological conditions, body size and composition, blood pressure, the augmentation index, carotid ultrasonography, an electrocardiogram, and biochemical indicators, as well as some novel factors, such as social network characteristics, exposure to environmental pollutants, inflammatory markers, hemostatic markers, and immunosenescence markers. Annual telephone interviews and follow-up health examinations at 5-year intervals after the baseline assessment are planned to collect information on changes in health status and its determinants. Additionally, indirect follow-up using secondary data sources will be conducted to obtain information on health services utilization and death. So far, more than 6,000 adults have been enrolled during the first three and a half years, and almost all participants have been tracked by annual telephone follow-up surveys. The data have been uploaded to iCReaT, the clinical research information management system of the Korea National Institute of Health.
MeSH Terms
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Adult
Blood Pressure
Body Size
Cardiovascular Diseases
Cohort Studies*
Electrocardiography
Environmental Pollutants
Follow-Up Studies
Health Behavior
Health Services
Humans
Immunosenescence
Information Management
Information Storage and Retrieval
Interviews as Topic
Korea
Metabolic Diseases*
Prospective Studies
Risk Factors
Telephone
Ultrasonography
Environmental Pollutants
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