J Korean Neurol Assoc.  2017 Nov;35(4):215-218. 10.17340/jkna.2017.4.6.

Narcolepsy Followed by Intractable Vomiting Caused by Recurrent Brain Involvement in Neuromyelitis Optica Spectrum Disorder

Affiliations
  • 1Department of Neurology, Pusan National University School of Medicine, Busan, Korea. yepark407@gmail.com
  • 2Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.

Abstract

We report a 26 year-old female who initially presented with hypersomnia and visual disturbance with preceding upper respiratory infection. She was diagnosed as neuromyelitis optica spectrum disorder (NMOSD) with the presence of anti-AQP4 antibody. Eight months later, she experienced nausea and vomiting refractory to conventional therapies, which was proved correlated with a lesion of area postrema on brain magnetic resonance imaging. These might be significant clinical manifestations in NMOSD and may widen the clinical spectrum of the disease.

Keyword

Neuromyelitis optica spectrum disorder; Hypersomnia; Vomiting

MeSH Terms

Area Postrema
Brain*
Disorders of Excessive Somnolence
Female
Humans
Magnetic Resonance Imaging
Narcolepsy*
Nausea
Neuromyelitis Optica*
Vomiting*
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