Soonchunhyang Med Sci.  2017 Dec;23(2):115-117. 10.0000/sms.2017.23.2.115.

A Case of Cerebral Salt Wasting Syndrome in Neuromyelitis Optica Spectrum Disorder

Affiliations
  • 1Department of Neurology, Inje University Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea. joongyangcho@gmail.com, jenhkpark@gmail.com

Abstract

Neuromyelitis optica spectrum disorder (NMOSD) may present with area postrema syndrome, which is characterized by intractable vomiting and hiccups. Hyponatremia is common in NMOSD and is mostly associated with the syndrome of inappropriate antidiuretic hormone secretion (SIADH). In contrast to SIADH, cerebral salt wasting syndrome (CSWS) causes hyponatremia, which is associated with severe natriuresis and extracellular volume depletion in patients with cerebral disease. To our knowledge, hyponatremia associated with CSWS has not been reported in a patient with NMOSD. Here, we describe a NMOSD presenting with hyponatremia, which may be caused by CSWS following area postrema syndrome.

Keyword

Cerebral salt wasting syndrome; Neuromyelitis optica; Intractable vomiting; Hyponatremia

MeSH Terms

Area Postrema
Hiccup
Humans
Hyponatremia
Inappropriate ADH Syndrome
Natriuresis
Neuromyelitis Optica*
Vomiting
Wasting Syndrome*
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