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Recent Updates on Narcolepsy and Hypersomnia

Hong S

Narcolepsy is a chronic neurological sleep disorder caused by hypocretin neuron loss, resulting in excessive daytime sleepiness, disturbed nocturnal sleep, and intrusions of aspects of rapid eye movement sleep in...
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Narcolepsy Followed by Intractable Vomiting Caused by Recurrent Brain Involvement in Neuromyelitis Optica Spectrum Disorder

Park YE, Jang JY, Kang YJ

We report a 26 year-old female who initially presented with hypersomnia and visual disturbance with preceding upper respiratory infection. She was diagnosed as neuromyelitis optica spectrum disorder (NMOSD) with the...
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Anti-Ma2-Associated Encephalitis Presenting as Hypersomnia

Jang JY, Park SW, Choi YJ, Kang YJ, Cho HJ, Kim J

Anti-Ma2-associated encephalitis is one of the paraneoplastic neurological syndromes. It has been shown to be associated with various neoplasms, mainly testicular, lung, and breast cancers. Most patients with anti-Ma2-associated encephalitis...
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The effect of aircraft noise on sleep disturbance among the residents near a civilian airport: a cross-sectional study

Kwak KM, Ju YS, Kwon YJ, Chung YK, Kim BK, Kim H, Youn K

BACKGROUND: Aircraft noise is a major environmental noise problem. This study was conducted in order to investigate the relationship between sleep disturbance and exposure to aircraft noise on the residents...
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CDH13 and HCRTR2 May Be Associated with Hypersomnia Symptom of Bipolar Depression: A Genome-Wide Functional Enrichment Pathway Analysis

Cho CH, Lee HJ, Woo HG, Choi JH, Greenwood , Kelsoe JR

Although bipolar disorder is highly heritable, the identification of specific genetic variations is limited because of the complex traits underlying the disorder. We performed a genome-wide association study of bipolar...
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Positive Sleep State Misperception Mimicking Hypersomnia

Jang CW, Ji KH

A condition of underestimation of sleep is classified as paradoxical insomnia or sleep state misperception. However, overestimation of sleep, so called positive sleep state misperception has not been clearly described....
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Hypersomnia as Presenting Symptom in Wilson's Disease

Jang JW, Park SY, Park YH, Yun CH, Kim JE, Kim S

Wilson's disease shows considerably various symptoms that sometimes timely diagnosis is delayed when patient shows vague clinical presentation. We present a female patient whose initial symptom was hypersomnia and severe...
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A Case of Atypical Kleine-Levin Syndrome

Seo JG, Seo SD, Park SP, Lee HW

  • KMID: 2202659
  • J Korean Sleep Res Soc.
  • 2013 Dec;10(2):56-58.
Kleine-Levin syndrome is characterized by recurrent episodes of hypersomnia and associated cognitive and behavioral impairments. We present a 47-year-old female patient with recurrent hypersomnia and disorder of appetite. During each...
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Morningness-Eveningness Affects the Depressive Mood and Day Time Sleepiness of Obstructive Sleep Apnea Syndrome Patient

Kim SH, Joo EJ, Lee KY, Koo YJ, Kim EJ

  • KMID: 2317522
  • Sleep Med Psychophysiol.
  • 2012 Dec;19(2):77-83.
OBJECTIVES: Recent studies have reported a correlation between obstructive sleep apnea syndrome (OSA) and depression. In attempt to verify the suggestion that eveningness is related to depression, we examined the...
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Narcolepsy: Clinical Feature, Diagnosis and Treatment

Shin HB

  • KMID: 2317492
  • Sleep Med Psychophysiol.
  • 2010 Dec;17(2):63-68.
Narcolepsy is a central neurologic system disease. It begins early in life with disabling symptoms including excessive daytime sleepiness, cataplexy, sleep paralysis, hypnagogic hallucination and nocturnal sleep fragmentation. Patient with...
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A Case of Recurrent Hypersomnia

Kang KH, Suh JG, Lee HW, Jung DK, Suh CK, Park SP

  • KMID: 1852269
  • J Korean Neurol Assoc.
  • 2005 Dec;23(6):833-835.
Recurrent hypersomnia is a disorder characterized by recurrent episodes of hypersomnia that typically occur weeks or months apart. We describe a 60-year-old woman with a four-year history of recurrent hypersomnia....
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Diagnosis and Treatment of Sleepiness

Cyn J

  • KMID: 2317385
  • Sleep Med Psychophysiol.
  • 2003 Jun;10(1):12-19.
Sleepiness, or hypersomnia, is a relatively common complaint and one of the main problems of modern society. Accurate evaluation and diagnosis of sleepiness are important. The methods used for evaluating...
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A Female Case of Kleine-Levin Syndrome Treated with Amantadine

Ahn JH, Han OS, Yu JC, Kim CY

  • KMID: 2340739
  • J Korean Neuropsychiatr Assoc.
  • 2002 Jul;41(4):725-732.
Kleine-Levin syndrome is a rare disorder which usually affects adolescent males and is characterized by periodic hypersomnia, hyperphagia and abnormal behavior. This is an unexplained clinical syndrome for which several...
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A Case of Seasonal Affective Disorder with Hypersomnia: Polysomnographic findings Before and After Light Therapy

Joe SH, Kim L, Suh KY

  • KMID: 2317313
  • Sleep Med Psychophysiol.
  • 1998 Dec;5(2):202-209.
Authors report the findings of nocturnal polysomnography and multiple sleep latency test(MSLT) before and after morning light treatment in a winter depressive patient with hypersomnia. On polysomnographic recordings the sleep...
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Successful Treatment of Five Cases of Idiopathic Central Nervous System Hypersomnia

Yoon IY, Jeong DU

  • KMID: 2317282
  • Sleep Med Psychophysiol.
  • 1997 Jun;4(1):89-95.
The authors studied 5 cases of idiopathic CNS hypersomnia who visited Division of Sleep Studies, Seoul National University Hospital in 1995. Detailed medical history was taken and nocturnal polysomnography(NPSG), multiple...
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Polysomnographic Findings in Kleine-Levin Syndrome

Lee SH

  • KMID: 2317265
  • Sleep Med Psychophysiol.
  • 1996 Jun;3(1):79-84.
Kleine-Levin syndrome is a disorder characterized by recurrent episodes of hypersomnia, hyperphagia and hypersexuality that typically occur weeks or months apart.A 17-years-old male showed these episodes and took nocturnal polysomnography(NPSG)...
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A Case of 24-Year-Old Woman with Recurrent Hypersomnic Complaint

Yoon IY, Jeong DU

  • KMID: 2317247
  • Sleep Med Psychophysiol.
  • 1995 Jun;2(1):91-96.
A 24-year-old woman complained of recurrent episodes of hypersomnia lasting on the average about 15 days with mild mood alternation such as depression and irritability. During inter episode interval, she...
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