J Clin Neurol.  2018 Jan;14(1):118-119. 10.3988/jcn.2018.14.1.118.

Wolff-Parkinson-White Syndrome in a Patient with Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes Syndrome Mimicking Juvenile Myoclonic Epilepsy

• Sung JH
• Han JH
• Kim H
• Kim JB

• KMID: 2399613
• DOI: http://doi.org/10.3988/jcn.2018.14.1.118

Abstract

No abstract available.

MeSH Terms

Acidosis, Lactic*
Brain Diseases*
Humans
Myoclonic Epilepsy, Juvenile*
Wolff-Parkinson-White Syndrome*

Figure

• 

  Fig. 1 A: Electrocardiography shows a short PR interval (96 msec) and QRS-complex widening (114 msec) with a delta wave. B: Electroencephalography shows 2–3 Hz frontal-dominant generalized polyspikes and wave discharges. C: Pedigree of the patient shows maternal inheritance traits. WPW: Wolff-Parkinson-White.

Reference

1. Sproule DM, Kaufmann P, Engelstad K, Starc TJ, Hordof AJ, De Vivo DC. Wolff-Parkinson-White syndrome in patients with MELAS. Arch Neurol. 2007; 64:1625–1627.

2. Lee MH, Sung YJ, Yoon JH, Kim J, Oh IY, Choi EK, et al. Wolff-Parkinson-White syndrome in a patient with mitochondrial encephalopathy, lactic acidosis and stroke-like episodes syndrome. Korean Circ J. 2011; 41:674–676.

3. Malfatti E, Laforêt P, Jardel C, Stojkovic T, Behin A, Eymard B, et al. High risk of severe cardiac adverse events in patients with mitochondrial m.3243A>G mutation. Neurology. 2013; 80:100–105.

4. Chevallier JA, Von Allmen GK, Koenig MK. Seizure semiology and EEG findings in mitochondrial diseases. Epilepsia. 2014; 55:707–712.

5. Lee HN, Eom S, Kim SH, Kang HC, Lee JS, Kim HD, et al. Epilepsy characteristics and clinical outcome in patients with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS). Pediatr Neurol. 2016; 64:59–65.