Korean J Anesthesiol.  2005 Sep;49(3):429-432. 10.4097/kjae.2005.49.3.429.

General Anesthesia with Sevoflurane for a Patient with MELAS (Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, Stroke-like Episodes) Syndrome: A case report

Affiliations
  • 1Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, Seoul, Korea. kimcs@snu.ac.kr

Abstract

We describe the anesthetic management of a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, stroke-like episodes (MELAS) syndrome, and a form of mitochondrial myopathy. A 14 year-old-male with MELAS syndrome underwent tracheostomy under general anesthesia. Anesthesia was managed with thiopental sodium, nitrous oxide, sevoflurane, and rocuronium. His reactions to anesthetics and muscle relaxant were within normal limits. No serious complication was observed. The implication of MELAS syndrome for anesthesia are discussed.

Keyword

complication; general anesthesia; MELAS syndrome; mitochondrial myopathy; sevoflurane

MeSH Terms

Acidosis, Lactic*
Anesthesia
Anesthesia, General*
Anesthetics
Humans
MELAS Syndrome*
Mitochondrial Myopathies
Muscular Diseases*
Nitrous Oxide
Thiopental
Tracheostomy
Anesthetics
Nitrous Oxide
Thiopental
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