J Korean Orthop Assoc.  2005 Oct;40(6):757-762.

Effect of Amniotic Membrane Transplantation on Tissue Adhesion in Flexor Tenorrhaphy of Chicken

Affiliations
  • 1Department of Orthopedic Surgery, College of Medicine, Dong-A University, Busan, Korea. tynitus@dau.ac.kr
  • 2Department of Pathology, College of Medicine, Dong-A University, Busan, Korea.

Abstract

PURPOSE
The role of the amniotic membrane with or without radiation was investigated with regard to preventing adhesion after flexor tenorrhaphy of chicken. MATERIALS AND METHODS: Nine chicken were divided into three groups. The second flexor tendon of the chicken was operated on. In group A, the flexor tendon was excised and one half and the tendon was repaired. In group B, the repaired tendon was covered with an amniotic membrane. In group C, the repaired tendon was covered with a lyophilised and 25 kGy irradiated amniotic membrane. The gross and histology findings on the level of inflammation and fibrosis of the repaired tendon were evaluated at 3, 6 and 9 weeks after surgery. RESULTS: Group C had the least inflammatory cell infiltration and fibroblast proliferation at any time. CONCLUSION: The use of radiated amniotic membrane was effective in preventing inflammation and adhesion after flexor tenorrhaphy in chickens.

Keyword

Flexor tenorrhaphy; Irradiated amniotic membrane; Tissue adhesion

MeSH Terms

Amnion*
Chickens*
Fibroblasts
Fibrosis
Inflammation
Tendons
Tissue Adhesions*
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