Korean J Vet Res.
2017 Sep;57(3):197-200. 10.14405/kjvr.2017.57.3.197.
Effects of dietary acetaminophen and vitamin C supplement on serum cortisol and tumor necrosis factor-alpha concentrations in pigs vaccinated with foot-and-mouth disease vaccine
- Affiliations
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- 1Engineering Research Institute and Department of Industrial Systems Engineering, Gyeongsang National University, Jinju 52828, Korea.
- 2College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Korea.
- 3Department of Medical Humanities and Social Medicine, College of Medicine, Kosin University, Busan 49267, Korea.
- 4Department of Computer Information, Gyeongnam Provincial Namhae College, Namhae 52422, Korea.
- 5College of Veterinary Medicine and Institute of Animal Medicine, Gyeongsang National University, Jinju 52828, Korea. hujang@gnu.ac.kr
- KMID: 2394911
- DOI: http://doi.org/10.14405/kjvr.2017.57.3.197
Abstract
- This study evaluated the effect of a combination of acetaminophen and vitamin C (CAV) on reducing serum cortisol and tumor necrosis factor-α (TNF-α) concentrations in piglets vaccinated with foot-and-mouth disease (FMD) vaccine. Piglets were vaccinated with FMD vaccine and treated with CAV at concentrations of 0.0, 0.5, 1.0, and 2.0 kg/ton feed (P-CON, AD-1, AD-2, and AD-3, groups, respectively) for 5 days post-vaccination. Cortisol and TNF-α levels at 5 days post-treatment in the AD-1-3 groups were significantly lower than that in the P-CON group (p < 0.05). There were no significant differences between AD-2 and AD-3 groups and non-vaccinated, non-CAV-treated piglets.
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