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Vitamin C restores ovarian follicular reservation in a mouse model of aging

Abdollahifar MA, Azad N, Sajadi E, Shams Mofarahe Z, Zare F, Moradi A, Rezaee F, Gholamin M, Abdi S

Ovarian aging is related to the reduction of oocyte quality and ovarian follicles reservation leading to infertility. Vitamin C is a natural antioxidant which may counteract with adverse effects of...
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The efficacy of vitamin C on postlaparoscopic shoulder pain: a double-blind randomized controlled trial

Moon S, Lim SH, Cho K, Kim MH, Lee W, Cho YH

BACKGROUND: This study evaluated the effect of vitamin C on post-laparoscopic shoulder pain (PLSP) in patients undergoing benign gynecological surgery during the first 72 h. METHODS: Sixty patients (aged 20 to...
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Role of ascorbic acid in dapsone induced methemoglobinemia

Sahu KK, Mishra AK

No abstract available.
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Therapeutic effect of ascorbic acid on dapsone-induced methemoglobinemia in rats

Kang C, Kim DH, Kim T, Lee SH, Jeong JH, Lee SB, Kim JH, Jung MH, Lee KW, Park IS

OBJECTIVE: Dapsone (diaminodiphenyl sulfone, DDS) is currently used to treat leprosy, malaria, dermatitis herpetiformis, and other diseases. It is also used to treat pneumocystis pneumonia and Toxoplasma gondii infection in...
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Relief of Acute Herpetic Pain by Intravenous Vitamin C: The Dosage May Make a Difference: Authors' Reply

Choi H, Na CH, Shin BS, Kim MS

No abstract available.
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Relief of Acute Herpetic Pain by Intravenous Vitamin C: The Dosage May Make a Difference

Wang LK, Chuang CC, Chen JY

No abstract available.
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Effect of vitamin C on azoxymethane (AOM)/dextran sulfate sodium (DSS)-induced colitis-associated early colon cancer in mice

Jeon HJ, Yeom Y, Kim YS, Kim E, Shin JH, Seok PR, Woo MJ, Kim Y

BACKGROUND/OBJECTIVES: The objective of this study was to investigate the effects of vitamin C on inflammation, tumor development, and dysbiosis of intestinal microbiota in an azoxymethane (AOM)/dextran sulfate sodium (DSS)-induced...
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Clinical Features of Herpes Simplex Keratitis in a Korean Tertiary Referral Center: Efficacy of Oral Antiviral and Ascorbic Acid on Recurrence

Kim GN, Yoo WS, Park MH, Chung JK, Han YS, Chung IY, Seo SW, Yoo JM, Kim SJ

PURPOSE: To describe the clinical manifestations of herpes simplex keratitis (HSK) in a tertiary referral center in South Korea and to determine whether ascorbic acid treatment prevents recurrence of herpetic...
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Comparison of Blueberry (Vaccinium spp.) and Vitamin C via Antioxidative and Epigenetic Effects in Human

Kim M, Na H, Kasai H, Kawai K, Li YS, Yang M

BACKGROUND: Chemopreventive effects and the underlying mechanisms of blueberry (Vaccinium spp.) are not clearly understood in human. We hypothesized blueberry would work via antioxidative and epigenetic modulation, which is similar...
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Effects of dietary acetaminophen and vitamin C supplement on serum cortisol and tumor necrosis factor-alpha concentrations in pigs vaccinated with foot-and-mouth disease vaccine

Cha CN, Lee BJ, Park EK, Yoo CY, Kim S, Lee HJ

This study evaluated the effect of a combination of acetaminophen and vitamin C (CAV) on reducing serum cortisol and tumor necrosis factor-α (TNF-α) concentrations in piglets vaccinated with foot-and-mouth disease...
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Split-dose Bowel Preparation for Colonoscopy: 2 Liters Polyethylene Glycol with Ascorbic Acid versus Sodium Picosulfate versus Oral Sodium Phosphate Tablets

Lee SW, Bang CS, Park TY, Suk KT, Baik GH, Kim DJ

BACKGROUND/AIMS: Adequate bowel preparation is an essential factor affecting the visibility of colonic mucosa and safety of related therapeutic interventions. The aim of this study was to assess the efficacy,...
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Effects of Vitamin C Supplementation on Plasma and Urinary Vitamin C Concentration in Korean Women

Choi J, Kim DY, Choue R, Lim H

Although vitamin C supplements were consumed for health maintenance and fatigue recovery, the effects of high doses of vitamin C supplement remains controversial. Our study performed the effects of 100...
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Enhancement of skin permeation of vitamin C using vibrating microneedles

Lee CA, Baek JS, Kwag DG, Lee HJ, Park J, Cho CW

This study was performed to evaluate the use of vibrating microneedles for the transdermal delivery of vitamin C. The microneedles were designed to vibrate at three levels of intensity. In...
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Effect of iron overload with ascorbic acid on experimental colon carcinogenesis in mice

Ahn TH, Kim SJ, Jeong JH, Nam SY, Yun YW, Lee BJ

Excessive iron can promote the production of free radicals, thereby leading to harmful effects on cancer and aging. Ascorbic acid is not only an antioxidant but also a co-factor of...
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A Case of a Herbicide Poisoning Induced Methemoglobinemia Patient Treated with High-dose Vitamin C

Sun KH, Kim JK, Ryu CY, Kim SJ, Jo HK, Yoo TH, Park YJ, Kim SP

Methemoglobinemia is a condition in which the iron portion of hemoglobin, which binds to oxygen, is oxidized to produce methemoglobin, which increases blood concentration. There are many causes of methemoglobinemia,...
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Associations among plasma vitamin C, epidermal ceramide and clinical severity of atopic dermatitis

Shin J, Kim YJ, Kwon O, Kim NI, Cho Y

BACKGROUND/OBJECTIVES: Atopic dermatitis (AD), a chronic inflammatory skin disease, is accompanied by disruption of the epidermal lipid barrier, of which ceramide (Cer) is the major component. Recently it was reported...
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Vitamin C is taken up by human T cells via sodium-dependent vitamin C transporter 2 (SVCT2) and exerts inhibitory effects on the activation of these cells in vitro

Hong JM, Kim JH, Kang JS, Lee WJ, Hwang YI

Vitamin C is an essential micronutrient that affects immune responses. T cells are one of the main players in acquired immunity and have been reported to be influenced by in...
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HPLC-UV method for the simultaneous determinations of ascorbic acid and dehydroascorbic acid in human plasma

Kim Y, Kim MG

A high performance liquid chromatography (HPLC) paired with UV-vis detection method to determine ascorbic acid and its oxidation product, dehydroascorbic acid, in human plasma was developed. Ascorbic acid in human...
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Combined treatment with minodronate and vitamin C increases bone mineral density and strength in vitamin C-deficient rats

Segawa T, Miyakoshi , Kasukawa Y, Aonuma H, Tsuchie H, Shimada Y

  • KMID: 2309513
  • Osteoporos Sarcopenia.
  • 2016 Mar;2(1):30-37.
OBJECTIVES: Reduced bone quality caused by vitamin C deficiency in older persons may lead to incidental fragility fractures during bisphosphonate treatment, although bisphosphonate increases bone mineral density (BMD). This study...
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Vitamin C and antioxidant capacity stability in cherry and romaine during storage at different temperatures

Park HJ, Lee MJ, Lee HR

PURPOSE: The aim of this work was to study the change in antioxidant activity depending on storage temperature and storage period in romaine and cherry. METHODS: The plant material was stored...
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