Obstet Gynecol Sci.  2017 Sep;60(5):455-461. 10.5468/ogs.2017.60.5.455.

Port site infiltration of local anesthetic after laparoendoscopic single site surgery for benign adnexal disease

Affiliations
  • 1Department of Obstetrics and Gynecology, Konkuk University School of Medicine, Seoul, Korea. 20130131@kuh.ac.kr

Abstract


OBJECTIVE
To determine whether local bupivacaine injection into the incision site after gynecologic laparoendoscopic single site surgery (LESS) improves postoperative pain.
METHODS
This prospective cohort study included consecutive 158 patients who had LESS for benign adnexal disease from March 2013 to December 2015. Chronologically, 82 patients (March 2013 to August 2014) received no bupivacaine (group 1) and 76 (August 2014 to December 2015) received a bupivacaine block (group 2). For group 2, 10 mL 0.25% bupivacaine was injected into the 20 mm-incision site through all preperitoneal layers after LESS completion. Primary outcome is postoperative pain score using the visual analog scale (VAS).
RESULTS
There was no difference in clinicopathological characteristics between the groups. Operating time (expressed as median [range], 92 [55-222] vs. 100 [50-185] minutes, P=0.137) and estimated blood loss (50 [30-1,500] vs. 125 [30-1,000] mL, P=0.482) were similar between the groups. Post-surgical VAS pain scores after 3 hours (3.5 [2-6] vs. 3.5 [2-5], P=0.478), 6 to 8 hours (3.5 [2-6] vs. 3 [1-8], P=0.478), and 16 to 24 hours (3 [2-4] vs. 3 [1-7], P=0.664) did not differ between groups.
CONCLUSION
Bupivacaine injection into the trocar site did not improve postoperative pain after LESS. Randomized trials are needed to evaluate the benefits of local bupivacaine anesthetic for postoperative pain reduction.

Keyword

Local anesthesia; Laparoscopy; Pain; Minimally invasive surgical procedures

MeSH Terms

Adnexal Diseases*
Anesthesia, Local
Bupivacaine
Cohort Studies
Female
Humans
Laparoscopy
Minimally Invasive Surgical Procedures
Pain, Postoperative
Prospective Studies
Surgical Instruments
Visual Analog Scale
Bupivacaine

Cited by  1 articles

The role of port site local anesthetic injection in laparoendoscopic single site surgery: a prospective randomized study
Jong Wook Seo, In Ok Lee, Jung Cheol Kim, Jae Eun Chung
Obstet Gynecol Sci. 2020;63(3):387-394.    doi: 10.5468/ogs.2020.63.3.387.


Reference

1. Medeiros LR, Rosa DD, Bozzetti MC, Fachel JM, Furness S, Garry R, et al. Laparoscopy versus laparotomy for benign ovarian tumour. Cochrane Database Syst Rev. 2009; CD004751. PMID: 19370607.
Article
2. Rattanalappaiboon D, Werawatakul Y, Tharnprisan P, Prasit M. Intraperitoneal lidocaine for decreasing intraoperative pain during postpartum tubal resection in Srinagarind Hospital. J Med Assoc Thai. 2012; 95:477–481. PMID: 22611998.
3. Gupta N, Dadhwal V, Mittal S. Combined intraperitoneal instillation and port site infiltration of local anaesthetic (bupivacaine) for postoperative analgesia in women undergoing daycare diagnostic gynaecological laparoscopy. Eur J Obstet Gynecol Reprod Biol. 2012; 161:109–110. PMID: 22153906.
Article
4. Yim GW, Lee M, Nam EJ, Kim S, Kim YT, Kim SW. Is single-port access laparoscopy less painful than conventional laparoscopy for adnexal surgery? A comparison of postoperative pain and surgical outcomes. Surg Innov. 2013; 20:46–54. PMID: 22410390.
Article
5. Lee YY, Kim TJ, Kim CJ, Park HS, Choi CH, Lee JW, et al. Single port access laparoscopic adnexal surgery versus conventional laparoscopic adnexal surgery: a comparison of peri-operative outcomes. Eur J Obstet Gynecol Reprod Biol. 2010; 151:181–184. PMID: 20392556.
Article
6. Behnia-Willison F, Foroughinia L, Sina M, McChesney P. Single incision laparoscopic surgery (SILS) in gynaecology: feasibility and operative outcomes. Aust N Z J Obstet Gynaecol. 2012; 52:366–370. PMID: 22548311.
Article
7. Fagotti A, Bottoni C, Vizzielli G, Gueli Alletti S, Scambia G, Marana E, et al. Postoperative pain after conventional laparoscopy and laparoendoscopic single site surgery (LESS) for benign adnexal disease: a randomized trial. Fertil Steril. 2011; 96:255–259.e2. PMID: 21565338.
Article
8. Takeda A, Imoto S, Mori M, Nakano T, Nakamura H. Isobaric laparoendoscopic single-site surgery with wound retractor for adnexal tumors: a single center experience with the initial 100 cases. Eur J Obstet Gynecol Reprod Biol. 2011; 157:190–196. PMID: 21470765.
Article
9. Escobar PF, Bedaiwy MA, Fader AN, Falcone T. Laparoendoscopic single-site (LESS) surgery in patients with benign adnexal disease. Fertil Steril. 2010; 93:2074.e7–2074.e10.
Article
10. Fader AN, Rojas-Espaillat L, Ibeanu O, Grumbine FC, Escobar PF. Laparoendoscopic single-site surgery (LESS) in gynecology: a multi-institutional evaluation. Am J Obstet Gynecol. 2010; 203:501.e1–501.e6. PMID: 20663487.
Article
11. Fader AN, Escobar PF. Laparoendoscopic single-site surgery (LESS) in gynecologic oncology: technique and initial report. Gynecol Oncol. 2009; 114:157–161. PMID: 19481243.
Article
12. Kim WC, Lee JE, Kwon YS, Koo YJ, Lee IH, Lim KT. Laparoendoscopic single-site surgery (LESS) for adnexal tumors: one surgeon's initial experience over a one-year period. Eur J Obstet Gynecol Reprod Biol. 2011; 158:265–268. PMID: 21620559.
Article
13. Hoyer-Sørensen C, Vistad I, Ballard K. Is single-port laparoscopy for benign adnexal disease less painful than conventional laparoscopy? A single-center randomized controlled trial. Fertil Steril. 2012; 98:973–979. PMID: 22769732.
Article
14. Teoh AY, Chiu PW, Wong TC, Poon MC, Wong SK, Leong HT, et al. A double-blinded randomized controlled trial of laparoendoscopic single-site access versus conventional 3-port appendectomy. Ann Surg. 2012; 256:909–914. PMID: 23154391.
Article
15. Prasad A, Mukherjee KA, Kaul S, Kaur M. Postoperative pain after cholecystectomy: conventional laparoscopy versus single-incision laparoscopic surgery. J Minim Access Surg. 2011; 7:24–27. PMID: 21197238.
Article
16. Tam T, Harkins G, Wegrzyniak L, Ehrgood S, Kunselman A, Davies M. Infiltration of bupivacaine local anesthetic to trocar insertion sites after laparoscopy: a randomized, double-blind, stratified, and controlled trial. J Minim Invasive Gynecol. 2014; 21:1015–1021. PMID: 24792311.
Article
17. Roy KK, Subbaiah M, Naha M, Kumar S, Sharma JB, Jahagirdar N. Intraperitoneal bupivacaine for pain relief after minilaparoscopy in patients with infertility. Arch Gynecol Obstet. 2014; 289:337–340. PMID: 23925646.
Article
18. Zupi E, Marconi D, Sbracia M, Solima E, Zullo F, Dauri M, et al. Is local anesthesia an affordable alternative to general anesthesia for minilaparoscopy? J Am Assoc Gynecol Laparosc. 2000; 7:111–114. PMID: 10648749.
Article
19. Zullo F, Pellicano M, Cappiello F, Zupi E, Marconi D, Nappi C. Pain control after microlaparoscopy. J Am Assoc Gynecol Laparosc. 1998; 5:161–163. PMID: 9564064.
Article
20. Pellicano M, Zullo F, Di Carlo C, Zupi E, Nappi C. Postoperative pain control after microlaparoscopy in patients with infertility: a prospective randomized study. Fertil Steril. 1998; 70:289–292. PMID: 9696223.
Article
21. Buck L, Varras MN, Miskry T, Ruston J, Magos A. Intraperitoneal bupivacaine for the reduction of postoperative pain following operative laparoscopy: a pilot study and review of the literature. J Obstet Gynaecol. 2004; 24:448–451. PMID: 15203590.
Article
22. Alexander JI. Pain after laparoscopy. Br J Anaesth. 1997; 79:369–378. PMID: 9389858.
Article
23. Marks JL, Ata B, Tulandi T. Systematic review and metaanalysis of intraperitoneal instillation of local anesthetics for reduction of pain after gynecologic laparoscopy. J Minim Invasive Gynecol. 2012; 19:545–553. PMID: 22763313.
Article
24. Einarsson JI, Sun J, Orav J, Young AE. Local analgesia in laparoscopy: a randomized trial. Obstet Gynecol. 2004; 104:1335–1339. PMID: 15572499.
Article
25. Ghezzi F, Cromi A, Bergamini V, Raffaelli R, Crotti S, Segredini R, et al. Preemptive port site local anesthesia in gynecologic laparoscopy: a randomized, controlled trial. J Minim Invasive Gynecol. 2005; 12:210–215. PMID: 15922977.
Article
26. Lam KW, Pun TC, Ng EH, Wong KS. Efficacy of preemptive analgesia for wound pain after laparoscopic operations in infertile women: a randomised, double-blind and placebo control study. BJOG. 2004; 111:340–344. PMID: 15008770.
Article
27. Savaris RF, Chicar LL, Cristovam RS, Moraes GS, Miguel OA. Does bupivacaine in laparoscopic ports reduce postsurgery pain in tubal ligation by electrocoagulation? A randomized controlled trial. Contraception. 2010; 81:542–546. PMID: 20472124.
Article
28. Mouton WG, Bessell JR, Otten KT, Maddern GJ. Pain after laparoscopy. Surg Endosc. 1999; 13:445–448. PMID: 10227938.
Article
29. Tsai HW, Wang PH, Yen MS, Chao KC, Hsu TF, Chen YJ. Prevention of postlaparoscopic shoulder and upper abdominal pain: a randomized controlled trial. Obstet Gynecol. 2013; 121:526–531. PMID: 23635614.
30. Alkhamesi NA, Peck DH, Lomax D, Darzi AW. Intraperitoneal aerosolization of bupivacaine reduces postoperative pain in laparoscopic surgery: a randomized prospective controlled double-blinded clinical trial. Surg Endosc. 2007; 21:602–606. PMID: 17180268.
Article
31. Ott DE, Reich H, Love B, McCorvey R, Toledo A, Liu CY, et al. Reduction of laparoscopic-induced hypothermia, postoperative pain and recovery room length of stay by pre-conditioning gas with the Insuflow device: a prospective randomized controlled multi-center study. JSLS. 1998; 2:321–329. PMID: 10036122.
32. Kahokehr A, Sammour T, Soop M, Hill AG. Intraperitoneal use of local anesthetic in laparoscopic cholecystectomy: systematic review and metaanalysis of randomized controlled trials. J Hepatobiliary Pancreat Sci. 2010; 17:637–656. PMID: 20393755.
Article
33. Howard FM. Endometriosis and mechanisms of pelvic pain. J Minim Invasive Gynecol. 2009; 16:540–550. PMID: 19835795.
Article
34. Saccardi C, Gizzo S, Vitagliano A, Noventa M, Micaglio M, Parotto M, et al. Peri-incisional and intraperitoneal ropivacaine administration: a new effective tool in pain control after laparoscopic surgery in gynecology: a randomized controlled clinical trial. Surg Endosc. 2016; 30:5310–5318. PMID: 27008577.
Article
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