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Evaluation of the efficacy of unipolar and bipolar spinal dorsal root ganglion radiofrequency thermocoagulation in the treatment of postherpetic neuralgia

Zhu J, Luo G, He Q, Yao M

Background: Different views have been proposed on the radiofrequency treatment modes and parameters of radiofrequency thermocoagulation of the spinal dorsal root ganglion for the treatment of postherpetic neuralgia (PHN). It...
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Comparison of treatment outcomes in chronic coccygodynia patients treated with ganglion impar blockade versus caudal epidural steroid injection: a prospective randomized comparison study

Sencan S, Yolcu G, Bilim S, Kenis-Coskun O, Gunduz OH

Background: Coccygodynia is one of the chronic, refractory painful musculoskeletal disorders. Interventional procedures are applied to patients unresponsive to initial treatment in coccygodynia. This study aims to compare the treatment...
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Outcomes of epidural steroids following percutaneous transforaminal endoscopic discectomy: a meta-analysis and systematic review

Song Y, Li C, Guan J, Li C, Wu H, Cheng X, Ling B, Zhang J

Background: Percutaneous transforaminal endoscopic discectomy (PTED) has been widely used in the treatment of lumbar degenerative diseases. Epidural injection of steroids can reduce the incidence and duration of postoperative pain...
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Prevalence and risk factors of low back and pelvic pain in women with rectus abdominis diastasis: a multicenter retrospective cohort study

Yuan S, Wang H, Zhou J

Background: To explore the association between low back pain (LBP) and pelvic pain (PP) and rectus abdominis diastasis (RAD) in postpartum women and identify the characteristics and risk factors. Methods: Women...
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The profile of musculoskeletal pain and its associations with sleep quality and depression during the COVID-19 in Turkey

Karatel M, Bulut ZI, Sari EO, Pelin Z, Yakut Y

Background: The current pandemic has affected people’s health multidimensionally. This study aims to investigate musculoskeletal pain, sleep quality, depression levels, and their relationships in individuals belonging to different age groups...
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Effects of cyanocobalamin and its combination with morphine on neuropathic rats and the relationship between these effects and thrombospondin-4 expression

Düzenli N, Ülker S, Şengül G, Kayhan B, Önal A

Background: Thrombospondin-4 (TSP4) upregulates in the spinal cord following peripheral nerve injury and contributes to the development of neuropathic pain (NP). We investigated the effects of cyanocobalamin alone or in combination...
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Pharmacological interactions between intrathecal pregabalin plus tianeptine or clopidogrel in a rat model of neuropathic pain

Lee HG, Kim YO, Choi JI, Han XH, Shin YU, Yoon MH

Background: There is still unmet need in treating neuropathic pain and increasing awareness regarding the use of drug combinations to increase the effectiveness of treatment and reduce adverse effects in...
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The efficacy of GABAergic precursor cells transplantation in alleviating neuropathic pain in animal models: a systematic review and meta-analysis

Askarian-Amiri S, Maleki SN, Alavi SNR, Neishaboori AM, Toloui A, Gubari MIM, Sarveazad A, Hosseini M, Yousefifard M

Background: Current therapies are quite unsuccessful in the management of neuropathic pain. Therefore, considering the inhibitory characteristics of GABA mediators, the present systematic review and meta-analysis aimed to determine the...
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Anti-nociceptive and anti-inflammatory activities of the essential oil isolated from Cupressus arizonica Greene fruits

Fakhri S, Jafarian S, Majnooni MB, Farzaei MH, Mohammadi-Noori E, Khan H

Background: Cupressus arizonica Greene is a coniferous tree with great importance in fragrance and pharmaceutical industries. Essential oils from C. arizonica (EC) have shown potential antioxidant, and anti-microbial activities. This...
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Steroid injections in pain management: influence on coronavirus disease 2019 vaccines

Hong SM, Park YW, Choi EJ

The coronavirus disease 2019 (COVID-19) pandemic, which has been rampant since the end of 2019, has evidently affected pain management in clinical practice. Fortunately, a COVID-19 vaccination program is currently in...
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Role of Glucose Breath Test for Small Intestinal Bacterial Overgrowth in Children and Adolescents With Functional Abdominal Pain Disorders in Korea

Lee J, Paik CN, Kim DB, Lee JM, Kim YJ, Choi SK, Cho YJ

  • KMID: 2523786
  • J Neurogastroenterol Motil.
  • 2022 Jan;28(1):78-85.
  • doi: 10.5056/jnm20231
Background/Aims Small intestinal bacterial overgrowth (SIBO) is expected in children and adolescents with functional abdominal pain disorders (FAPDs). This study is conducted to estimate the prevalence of SIBO and to investigate...
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Efficacy of Acotiamide on Postprandial Distress Syndrome and Epigastric Pain Syndrome Depending on the Estimated Gastric Acid Secretion Level

Suzuki T, Ohba R, Kataoka E, Kudo Y, Zeniya A, Segawa D, Oikawa K, Odashima M, Saga T, Kuramitsu T, Sasahara H, Yoneyama K, Tomita T, Shimodaira Y, Iijima K

  • KMID: 2523783
  • J Neurogastroenterol Motil.
  • 2022 Jan;28(1):53-61.
  • doi: 10.5056/jnm20190
Background/Aims Gastric acid secretion is suspected to be a pivotal contributor to the pathogenesis of functional dyspepsia. The present study investigates the potential association of the gastric acid secretion estimated by...
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Effect of Sodium Alginate on Gastrointestinal Symptoms after Esophagogastroduodenoscopy with Biopsy: Randomized Controlled Trial

Nam SY, Lee SW, Jeon SW, Kwon YH

Background/Aims: After esophagogastroduodenoscopy (EGD) with biopsy, some patients experience gastrointestinal symptoms. This study investigated the effect of sodium alginate on biopsy-related gastrointestinal symptoms. Methods: In this open-label, randomized, controlled trial, patients...
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A problem-based approach in musculoskeletal ultrasonography: heel pain in adults

Kim YH, Chai JW, Kim DH, Kim HJ, Seo J

Musculoskeletal ultrasonography (US) has unique advantages, such as excellent spatial resolution for superficial structures, the capability for dynamic imaging, and the ability for direct correlation and provocation of symptoms. For...
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Effect of secondhand smoking on gingival pain and bleeding in non-smoking adolescents in South Korea

Choi MJ, Kim SY, Jang HY

Objectives: This study aimed to identifying the relationship between exposure to secondhand smoking and oral diseases in adolescents, based on the web-based youth health risk behavior survey from 2020. Methods: Among...
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Nasal packing with bupivacaine during nasotracheal intubation can reduce intubation-related epistaxis

Yu HK, Park J, Kang YH, Park HB, Bae SI, Lee SH, Ok SH, Jeong SH, Park M

Epistaxis often is caused by nasal mucosal damage and vascular injury after nasotracheal (NT) intubation. Bupivacaine constricts blood vessels at low concentrations and dilates them at high concentrations. In this...
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Incidence of Chronic Periscapular Pain After Adult Thoracolumbar Deformity Correction and Impact on Outcomes

Haddad AF, Scheer JK, Fury MT, Smith JS, Deviren V, Ames CP

Objective: Extension of the posterior upper-most instrumented vertebra (UIV) into the upper thoracic (UT) spine allows for greater deformity correction and reduced incidence of proximal junction kyphosis (PJK) in adult...
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Expression of vesicular glutamate transporter in transient receptor potential vanilloid 1-positive neurons in the rat trigeminal ganglion

Han HM, Cho YS, Bae YC

Activation of transient receptor potential vanilloid 1 (TRPV1), a calcium permeable channel expressed in primary sensory neurons, induces the release of glutamate from their central and peripheral afferents during normal...
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Chewing gum as a non-pharmacological alternative for orthodontic pain relief: A randomized clinical trial using an intention-to-treat analysis

Silva Santos DJd, Capelli Jr J

Objective: To compare the effectiveness of ibuprofen, acetaminophen, and chewing gum for orthodontic pain relief and to assess if chewing gum can be a non-pharmacological alternative for orthodontic pain relief....
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Effectiveness of low-level laser therapy and chewing gum in reducing orthodontic pain:  A randomized controlled trial

Celebi F, Bicakci AA, Kelesoglu U

Objective: The purpose of this study was to evaluate the effects of chewing gum and low-level laser therapy in alleviating orthodontic pain induced by the initial archwire. Methods: Patients with...
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