Clin Exp Vaccine Res.  2017 Jul;6(2):95-103. 10.7774/cevr.2017.6.2.95.

Recent outbreaks of highly pathogenic avian influenza viruses in South Korea

• Kim HK
• Jeong DG
• Yoon SW

• KMID: 2391569
• DOI: http://doi.org/10.7774/cevr.2017.6.2.95

Abstract

Outbreaks of H5 highly pathogenic avian influenza viruses (HPAIVs) have caused economic loss for the poultry industry and posed a threat to public health. In South Korea, novel reassortants of HPAIVs such as H5N6 and H5N8 had been circulating in poultry. Here, we will discuss the identity of recent novel reassortants of Korean H5 HPAIVs and the recent advances in vaccine development, which will be useful for controlling HPAIV transmission in poultry and for effectively preventing future epidemics and pandemics.

Keyword

Avian influenza; H5N1 subtype; H5N6 subtype; H5N8 subtype; Epidemiology; Vaccines

MeSH Terms

Animals
Disease Outbreaks*
Epidemiology
Influenza in Birds*
Korea*
Pandemics
Poultry
Public Health
Vaccines
Vaccines

Figure

• 

  Fig. 1 Predicting the evolution of Chinese H5Nx viruses. A genealogical tree of hemagglutinin sequences of H5Nx viruses by 2014 in China and H5N6 highly pathogenic avian influenza virus (HPAIV), 2016 in Korea. Nodes are colored according to the fitness ranking. Overall amino acids similarities of the input sequences were 86.2%-98.4%, while those of the lineage to which Korean H5N6 virus belonged were 97.5%-98.4%. A box indicates a H5N6 HPAIV in Korea, 2016.

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