J Vet Sci.  2018 Nov;19(6):850-854. 10.4142/jvs.2018.19.6.850.

Novel reassortants of clade 2.3.4.4 H5N6 highly pathogenic avian influenza viruses possessing genetic heterogeneity in South Korea in late 2017

• Lee YN
• Cheon SH
• Kye SJ
• Lee EK
• Sagong M
• Heo GB
• Kang YM
• Cho HK
• Kim YJ
• Kang HM
• Lee MH
• Lee YJ

• KMID: 2427035
• DOI: http://doi.org/10.4142/jvs.2018.19.6.850

Abstract

Novel H5N6 highly pathogenic avian influenza viruses (HPAIVs) were isolated from duck farms and migratory bird habitats in South Korea in November to December 2017. Genetic analysis demonstrated that at least two genotypes of H5N6 were generated through reassortment between clade 2.3.4.4 H5N8 HPAIVs and Eurasian low pathogenic avian influenza virus in migratory birds in late 2017, suggesting frequent reassortment of clade 2.3.4.4 H5 HPAIVs and highlighting the need for systematic surveillance in Eurasian breeding grounds.

Keyword

H5N6; H5N8; clade 2.3.4.4; highly pathogenic avian influenza; reassortment

MeSH Terms

Agriculture
Animals
Birds
Breeding
Ducks
Ecosystem
Genetic Heterogeneity*
Genotype
Influenza in Birds*
Korea*

Figure

• 

  Fig. 1 Schematic diagram of reassortment among clade 2.3.4.4b highly pathogenic avian influenza viruses (HPAIVs) in Eurasia. Each oval represents a viral isolate, within which the eight gene segments (from the top to the bottom: PB2, PB1, PA, HA, NP, NA, M, and NS) are indicated by horizontal bars. The color of each bar identifies its origin. The H5N8 B1 ancestor is indicated by light green. The original genes of the B0 ancestor are shown in gray. Other colors represent different Eurasian avian influenza lineages.

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