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A Nationwide Survey on the Hospital Vaccination Policies in Korea

Park SH, Lee MS, Kim SR, Kwak YG

BACKGROUND: Healthcare personnel (HCP) are at risk of being exposed to or transmitting infections in hospitals, and vaccination against vaccine-preventable diseases (VPDs) is a well-known preventive strategy. Vaccination against influenza,...
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Signal Detection of Adverse Events Following Pneumococcal Vaccines from the Korea Adverse Event Reporting System Database, 2005–2016

Kim KS, Oh IS, Kim HJ, Song I, Park MS, Shin JY

PURPOSE: We aimed to analyze the surveillance reports of adverse events (AEs) due to different types of pneumococcal vaccines, in addition to detecting and validating signals of pneumococcal vaccines by...
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Delayed-Onset Anaphylaxis Caused by IgE Response to Influenza Vaccination

Kim MJ, Shim DH, Cha HR, Kim CB, Kim SY, Park JH, Sohn MH, Lee JM, Kim KW

Influenza vaccine-associated anaphylaxis is a very rare allergic reaction to vaccines, but the most concerning and life-threatening adverse reaction. Although the safety of influenza vaccines has been well documented, occasional...
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Updates of adult immunization in Korea

Shin HY, Yoo BW

An increase in the number of patients with infectious diseases in Korea, can be attributed to various factors, such as the prevalence of new infectious diseases of the 21st century,...
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Influenza Vaccine Effectiveness among Elementary School Students in Korea during the 2016-2017 Seasons: a Cross-Sectional Survey

Kim YM, Kang S, Lim JS, Kim DH

BACKGROUND: Annual vaccination is the principal way to reduce the mortality and morbidity associated with influenza. In the 2016–2017 influenza seasons, the influenza epidemic appeared to exhibit a different pattern...
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Comparison of antigenic mutation during egg and cell passage cultivation of H3N2 influenza virus

Park YW, Kim YH, Jung HU, Jeong OS, Hong EJ, Kim H, Lee JI

PURPOSE: When influenza viruses are cultured in eggs, amino acid mutations of the hemagglutinin may occur through egg adaptation. On the other hand, when influenza viruses are cultured in animal...
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Immunogenicity of a new, inactivated canine adenovirus type 2 vaccine for dogs

Yang DK, Kim HH, Yoo JY, Ji M, Han BH, Oh S, Hyun BH

PURPOSE: We constructed a new canine adenovirus type 2 (CAV-2) vaccine candidate using the recently isolated Korean CAV-2 strain; we termed the vaccine APQA1701-40P and evaluated its safety and immunogenicity...
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The potential efficacy of the E2-subunit vaccine to protect pigs against different genotypes of classical swine fever virus circulating in Vietnam

Tran HT, Truong DA, Ly VD, Vu HT, Hoang TV, Nguyen CT, Chu NT, Nguyen VT, Nguyen DT, Miyazawa K, Kokuho T, Dang HV

PURPOSE: To date, many kinds of classical swine fever (CSF) vaccines have been developed to protect against this disease. However, the efficacy of these vaccines to protect the pig against...
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Reverse vaccinology approach for the identification and characterization of outer membrane proteins of Shigella flexneri as potential cellular- and antibody-dependent vaccine candidates

Leow CY, Kazi A, Hisyam Ismail CMK, Chuah C, Lim BH, Leow CH, Banga Singh KK

PURPOSE: In the developing world, bacillary dysentery is one of the most common communicable diarrheal infections. There are approximately 169 million cases of shigellosis reported worldwide. The disease is transmitted...
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Cold chain time- and temperature-controlled transport of vaccines: a simulated experimental study

Ng CZ, Lean YL, Yeoh SF, Lean QY, Lee KS, Suleiman A, Liew KB, Kassab YW, Al-Worafi , Ming LC

PURPOSE: The objective of this research was to examine the cold chain temperature maintenance for the supply of vaccines and other biological products by pharmaceutical wholesaler. MATERIALS AND METHODS: In this...
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Bordetella bronchiseptica is a potent and safe adjuvant that enhances the antigen-presenting capability of dendritic cells

Lee YJ, Han Y, Joo HG

We previously demonstrated that Bordetella bronchiseptica (B. bronchiseptica) antigen (Ag) enhances the Mycoplasma hyopneumoniae Ag-specific immune response. The focus of this study was whether acellular bacterin of B. bronchiseptica could...
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Verification with the utility of an established rapid assessment of brain safety for newly developed vaccines

Kim GH, Yi SS

In the twenty-first century, high contagious infectious diseases such as SARS (Severe Acute Respiratory Syndrome), MERS (Middle East Respiratory Syndrome), FMD (Foot-and-Mouth Disease) and AI (Avian Influenza) have become very...
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Aging and the Immune System: the Impact of Immunosenescence on Viral Infection, Immunity and Vaccine Immunogenicity

Oh SJ, Lee JK, Shin OS

Immunosenescence is characterized by a progressive deterioration of the immune system associated with aging. Multiple components of both innate and adaptive immune systems experience aging-related changes, such as alterations in...
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Non-Mandatory Influenza Vaccination Rates among Healthcare Workers during the 2017–2018 Influenza Season: a Multicenter Study in Korea

Kang JM, Lee J, Park YS, Park Y, Kwak YG, Song JE, Choi YJ

PURPOSE: Annual influenza vaccination is the best strategy to prevent healthcare-associated influenza transmission. Influenza vaccination rates among healthcare workers (HCWs) vary by country, region, and year. We investigated the influenza...
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Comparison of Split versus Subunit Seasonal Influenza Vaccine in Korean Children over 3 to under 18 Years of Age

Kang S, Kim DH, Eun BW, Kim NH, Kang EK, Lee BS, Kim YK

PURPOSE: This study was conducted to compare immunogenicities and reactogenicities of the trivalent inactivated subunit influenza vaccine and split influenza vaccine in Korean children and adolescents. METHODS: In total, 202 healthy...
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Issues on Current HPV Vaccination in Korea and Proposal Statement

Lee KE

No abstract available.
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Evaluation of Waning Immunity at 6 Months after Both Trivalent and Quadrivalent Influenza Vaccination in Korean Children Aged 6–35 Months

Lee JH, Cho HK, Kim KH, Lee J, Kim YJ, Eun BW, Kim NH, Kim DH, Jo DS, Kim HM, Kim YK

BACKGROUND: The titer of influenza vaccine-induced antibodies declines over time, and younger children have lower immunogenicity and shorter duration of immunity. This study aimed to compare persistence of antibody at...
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Production of polyclonal antibody against kidney antigens: a model for studying autoantibody in feline chronic kidney diseases

Songaksorn N, Petsophonsakul W, Pringproa , Lampang KN, Sthitmatee N, Sriphawattana N, Thongkorn

Chronic kidney disease is considered to be most common in geriatric domestic cats. It has been reported that the feline viral rhinotracheitis, calicivirus, and panleukopenia (FVRCP) vaccine prepared from the...
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Enhancement of antigen-specific humoral immune responses and protein solubility through conjugation of bacterial flagellin, Vibrio vulnificus FlaB, to the N-terminus of porcine epidemic diarrhea virus surface protein antigen S0

Oh SH, Kim Cho YS, Lee HB, Lee SM, Kim WS, Hong L, Cho CS, Choi YJ, Kang SK

Porcine epidemic diarrhea (PED) is a highly contagious enteric swine disease. The large economic impact of PED on the swine industry worldwide has made the development of an effective PED...
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Immunogenicity and efficacy of Schmallenberg virus envelope glycoprotein subunit vaccines

Endalew AD, Faburay B, Trujillo J, Gaudreault NN, Davis AS, Shivanna V, Sunwoo SY, Ma W, Drolet BS, McVey DS, Morozov I, Wilson WC, Richt JA

The Schmallenberg virus (SBV) is an orthobunyavirus that causes abortions, stillbirths, and congenital defects in pregnant sheep and cattle. Inactivated or live attenuated vaccines have been developed in endemic countries,...
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