Korean J Crit Care Med.  2017 Aug;32(3):302-305. 10.4266/kjccm.2017.00108.

An Ofloxacin-Induced Anaphylaxis through an IgG4-Mediated but Not IgE-Mediated Basophil Activation Mechanism

• Kim JH
• Seo DH
• Ban GY
• Yang EM
• Shin YS
• Ye YM
• Park HS

• KMID: 2391192
• DOI: http://doi.org/10.4266/kjccm.2017.00108

Abstract

No abstract available.

MeSH Terms

Anaphylaxis*
Basophils*

Figure

• 

  Figure 1. Detection of serum specific IgG4 antibodies to ofloxacin-human serum albumin (HSA) conjugate by ELISA from the patient (●) and 20 non-atopic normal controls (○). OD: optical density; ELISA: enzyme-linked immunosorbent assay.

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  Figure 2. Results of basophil activation test with addition of ofloxacin-human serum albumin (HSA) conjugate (A) and anti-IgG4 antibodies (B) in the patient (●) and three healthy controls (◇, △, ∇).

Reference

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