J Korean Burn Soc.  2017 Jun;20(1):12-15. 10.0000/jkbs.2017.20.1.12.

Clinical Effectiveness of a Newly Developed Collagen Substitute (InsureGraf®)

• Kim J
• Yoon JC
• Kim YM
• Lim HJ
• Kim D
• Hur J
• Chun W
• Cho YS

• KMID: 2385867
• DOI: http://doi.org/10.0000/jkbs.2017.20.1.12

Abstract

PURPOSE
Aim of this study was to assess effects of InsureGraf® (SK-Bioland Co., Korea), an artificial dermis developed by using tissue engineering technology in severe burn patients.
METHODS
To examine the clinical effectiveness of InsureGraf®, we transplanted them in patients with severe burns. A total of 14 joint regions in 8 patients received InsureGraf® graft selectively from July to December, 2014. The graft results were determined after confirming the take rate of the transplanted skin graft on top of the InsureGraf®. Take rates were examined twice, at 7 and 14 days after grafting. Photographs of the skin grafts were evaluated individually by two burn surgeon specialists, and the mean values were recorded.
RESULTS
The take rate was 99% after day 7 and 100% after day 14 respectively.
CONCLUSION
InsureGraf® can be used successfully as an artificial dermis that allows one-stage operation in severe burn patients, exhibiting a successful early-stage graft take rate that is close to 100%.

Keyword

InsureGraf®; Artificial dermis; Burn

MeSH Terms

Burns
Collagen*
Dermis
Humans
Joints
Skin
Specialization
Tissue Engineering
Transplants
Treatment Outcome*
Collagen