J Korean Diabetes.  2017 Jun;18(2):102-108. 10.4093/jkd.2017.18.2.102.

Diagnosis of Non-Alcoholic Fatty Liver Disease Based on Clinical and Laboratory Data

Affiliations
  • 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. yholee@yuhs.ac

Abstract

Non-alcoholic fatty liver disease (NAFLD) is one of the most common metabolic liver disorders, and its incidence is expected to increase rapidly in the future as the rate of obesity increases and populations age. The gold standard for diagnosing NAFLD is liver biopsy, which involves sample error, high cost, and can be complicated due to its invasive nature. Therefore, many studies have been reported to establish accurate and convenient models to detect NAFLD using clinical and laboratory parameters. Most were derived from relatively small number of subjects and lack external validation, especially in the Korean population. This article summarizes the established and emerging risk factors for NAFLD and reviews non-invasive diagnostic algorithms for NAFLD including hepatic fibrosis.

Keyword

Diagnosis; Liver cirrhosis; Non-alcoholic fatty liver disease

MeSH Terms

Biopsy
Diagnosis*
Fibrosis
Incidence
Liver
Liver Cirrhosis
Non-alcoholic Fatty Liver Disease*
Obesity
Risk Factors
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