Korean J Anesthesiol.  2017 Jun;70(3):345-349. 10.4097/kjae.2017.70.3.345.

Successful early application of extracorporeal membrane oxygenation to support cardiopulmonary resuscitation for a patient suffering from severe malignant hyperthermia and cardiac arrest: a case report

Affiliations
  • 1Department of Anesthesiology and Pain Medicine, Korea University College of Medicine, Seoul, Korea. yoonsz70@gmail.com
  • 2Department of Thoracic and Cardiovascular Surgery, Korea University College of Medicine, Seoul, Korea.

Abstract

Malignant hyperthermia (MH) may lead to metabolic crisis of skeletal muscle in susceptible individuals following exposure to triggering agents such as volatile anesthetics or depolarizing muscle relaxants. MH is a rare and a potentially lethal disease, which can lead to cardiac arrest. We report a case of severe MH, in which the rapidly evolving signs of hypermetabolism eventually resulted in cardiac arrest. Despite conventional treatments following cardiopulmonary resuscitation, the patient's vital signs did not improve. Therefore, we applied extracorporeal membrane oxygenation for providing hemodynamic support.

Keyword

Dantrolene; Desflurane; Extracorporeal membrane oxygenation; Malignant hyperthermia

MeSH Terms

Anesthetics
Cardiopulmonary Resuscitation*
Dantrolene
Extracorporeal Membrane Oxygenation*
Heart Arrest*
Hemodynamics
Humans
Malignant Hyperthermia*
Muscle, Skeletal
Neuromuscular Depolarizing Agents
Vital Signs
Anesthetics
Dantrolene
Neuromuscular Depolarizing Agents
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