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Sugammadex: clinical development and practical use

Fuchs-Buder T, Meistelman C, Raft J

Sugammadex is belonging to a new class of drugs: the selective relaxant binding agents. Sugammadex can reverse residual paralysis by encapsulating free circulating non depolarizing muscle relaxants. The mains advantages...
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Anesthetic Management for Thymectomy in the Patients with Myasthenia Gravis-Eight cases report

Lee SH, Lee SM, Cho SD, Song NW, Lee KH

Myasthenia Gravis is a chronic disorder of neuromuscular transmission characterized by weakness, fatigue of voluntary muscles, especially exacerbations and remissions, a rare disease in Korea. Special considerations are required...
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Epidural anesthesia for a lumbar discectomy in a patient with paramyotonia congenita: A case report

Kim KW, Park JC, Kim HJ

Paramyotonia congenita is a rare hereditary skeletal muscle disease characterized by exercise- or cold-induced myotonia. Anesthesiologists should make any efforts to prevent perioperative myotonic attack and muscle weakness in patients...
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Anesthetic Experience for Thymectomy in the Patient with Myasthenia Gravis Associatied with Thymoma

Jin YH, Bang GM

Efforts from various approaches have been made to anesthetize myasthenic patients associated with thymoma and, on a ehoice of kinds and dosage of the muscle relaxants, there were considerable solicitude...
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Malignant hyperthermia during cesarean section: A case report

Lee WJ, Lee JS

  • KMID: 2169200
  • Anesth Pain Med.
  • 2011 Jan;6(1):79-84.
Malignant hyperthermia is manifestated in susceptible individuals exposed to triggering drugs, such as depolarizing muscle relaxants and inhalational anesthetics. Various musculoskeletal abnormalities, such as scoliosis, hernias and strabismus, have been...
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Successful early application of extracorporeal membrane oxygenation to support cardiopulmonary resuscitation for a patient suffering from severe malignant hyperthermia and cardiac arrest: a case report

Huh H, Jung JS, Park SJ, Park MK, Lim CH, Yoon SZ

Malignant hyperthermia (MH) may lead to metabolic crisis of skeletal muscle in susceptible individuals following exposure to triggering agents such as volatile anesthetics or depolarizing muscle relaxants. MH is a...
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Malignant Hyperthermia during General Anesthesia

Kim TW, Chung HK, Kyoun IS

Malignant hyperthermia is a genetically transmitted, catastrophic, hypermetabolic syndrome that is induced by potent volatile anesthetics and/or depolarizing muscle relaxants. It is now well established that the pathophysiology is related...
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A suspicious case of malignant hyperthermia during general anesthesia with desflurane: A case report

Cho YS, Kim JH, Kim KW, Lee SI, Kim JY, Kim KT, Choe WJ, Park JS, Kim JW

  • KMID: 1795954
  • Anesth Pain Med.
  • 2013 Jul;8(3):171-174.
Malignant hyperthermia (MH) is an inherited disorder of skeletal muscle manifested as a life threatening hypermetabolic crisis in susceptible individuals following exposure to commonly used inhaled anesthetics and depolarizing muscle...
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Effects of Lidocaine on the Dose-Response Curve of Cisatracurium

Oh EJ, Lim YJ, Hong JG, Yang HS

BACKGROUND: Lidocaine is useful as a local anesthetic and antiarrhythmic agent perioperatively. It may augment a neuromuscular block from both nondepolarizing and depolarizing muscle relaxants. Cisatracurium is a new...
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Anesthetic experience for patients with malignant hyperthermia susceptibility determined by molecular genetic test: A report of 2 cases

Lee JW, Yi JS, Lee JR, Kim DC

Malignant hyperthermia (MH) is a potentially fatal pharmacogenetic disorder manifested as a life threatening hypermetabolic crisis in susceptible individuals following exposure to inhalation anesthetics and to depolarizing muscle relaxants. The...
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Effects of Lidocaine on the Neuromuscular Block of Cisatracurium and Rocuronium

Lee EJ, Lim YJ, Gwak MJ, Yang HS

BACKGROUND: Lidocaine is a useful local anesthetic and antiarrhythmic agent perioperatively. It may augment a neuromuscular block from both nondepolarizing and depolarizing muscle relaxants. Cisatracurium of benzylisoquinoline derivatives...
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Early Recognition of Malignant Hyperthermia with Capnography: A case report

Kim DC, Lim HR, Han YJ

Malignant hyperthemia is an autosomal-dominant inherited disorder of the skeletal muscle cell charac terized by a hypermetabolic response to all commonly used inhalational anesthetics and depolarizing muscle relaxants. The clinical...
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Reevaluation by Clinical Grading Scale for Malignant Hyperthermia Reported in Korean Journal of Anesthesiology

Lee JW, Moon SS, Lee JR, Kim DC

BACKGROUND: Malignant hyperthermia (MH) is a disorder of the skeletal muscle manifested as a life threatening hypermetabolic crisis in susceptible individuals following exposure to inhalation anesthetics and depolarizing muscle relaxants....
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Identification of G7304A Mutation in the Ryanodine Receptor Type 1 Gene in a Patient with Malignant Hyperthermia and an Extended Pedigree Study in a Korean Malignant Hyperthermia Family

Kim DC, Kim DS

BACKGROUND: Malignant hyperthermia (MH) is a disorder of the skeletal muscle manifested as a life threatening hypermetabolic crisis in susceptible individuals following exposure to inhalation anesthetics and depolarizing muscle relaxants....
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