Intest Res.  2017 Jul;15(3):380-387. 10.5217/ir.2017.15.3.380.

Ophthalmologic manifestations in patients with inflammatory bowel disease

• Lee HJ
• Song HJ
• Jeong JH
• Kim HU
• Boo SJ
• Na SY

• KMID: 2382382
• DOI: http://doi.org/10.5217/ir.2017.15.3.380

Abstract

BACKGROUND/AIMS
Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), has been reported to have various ophthalmologic manifestations. The aim of this study was to evaluate the prevalence of ophthalmologic manifestations associated with IBD in Korea.
METHODS
Sixty-one patients were examined between May 2013 and October 2014. We performed complete ophthalmologic examinations.
RESULTS
Findings included 36 patients with CD and 25 with UC. The mean age of the patients was 34±16 years and disease duration was 45.3±23.9 months. Ophthalmologic manifestations were positive in 44 cases. Primary complication was diagnosed in 5 cases, as follows; iritis in 2 cases, episcleritis in one case, iritis with optic neuritis in 1 case, and serous retinal detachment in 1 case, without secondary complications. The most common coincidental complication was dry eye syndrome (DES), in 35 patients (57.4%). The prevalence of DES in the control group was 21.3%. The proportion of DES in patients with IBD was significantly higher than in the control group (P=0.002).
CONCLUSIONS
Ophthalmologic manifestations were high (72.1%) in IBD patients. Clinically significant primary ocular inflammation occurred in 8.2% of patients. The most common complication was DES. There was a higher rate of DES in patients with IBD compared to the control group. Evaluation of the eye should be a routine component in patients with IBD.

Keyword

Inflammatory bowel disease; Crohn disease; Colitis, ulcerative; Ophthalmology; Dry eye syndromes

MeSH Terms

Colitis, Ulcerative
Crohn Disease
Dry Eye Syndromes
Humans
Inflammation
Inflammatory Bowel Diseases*
Iritis
Korea
Ophthalmology
Optic Neuritis
Prevalence
Retinal Detachment
Scleritis

Figure

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  Fig. 1 Anterior segment photograph of a 76-year-old female patient with UC. This picture shows severe iritis in the left eye.

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