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Agreement Level of Inflammatory Bowel Disease Symptom Reports between Children and Their Parents

Vernon-Roberts A, Rouse E, Bowcock NL, Lemberg DA, Day AS

Purpose: Children with inflammatory bowel disease (IBD) frequently undergo clinical assessments, involving triadic communication between clinician, parent, and child. During such encounters parents are traditionally the main communicator of information...
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De-escalation of Therapy in Patients with Quiescent Inflammatory Bowel Disease

Miyatani Y, Kobayashi T

Inflammatory bowel disease is a chronic disease of unknown origin that requires long-term treatment. The optical duration of maintenance treatment once remission has been achieved remains unclear. When discussing a...
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Bone Mineral Density in Patients with Pediatric Inflammatory Bowel Disease Using Dual Energy X-Ray Absorptiometry

Isa HM, Ezzaldin AA, Alabbasi MM, ALaazmi NH, Masood AS, Alabbasi HM

Background: Inflammatory bowel disease (IBD) is a chronic inflammatory immune-mediated condition that affects the gastrointestinal system and alters bone growth and bone mineral density (BMD). Here we aimed to study...
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Inflammatory bowel disease–associated intestinal fibrosis

Park JM, Kim J, Lee YJ, Bae SU, Lee HW

Fibrosis is characterized by a proliferation of fibroblasts and excessive extracellular matrix following chronic inflammation, and this replacement of organ tissue with fibrotic tissue causes a loss of function. Inflammatory...
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Rising Burden of Psychiatric and Behavioral Disorders and Their Adverse Impact on Health Care Expenditure in Hospitalized Pediatric Patients with Inflammatory Bowel Disease

Thavamani A, Khatana J, Umapathi KK, Sankararaman S

Purpose: The incidence and prevalence of inflammatory bowel disease (IBD) are increasing along with an increasing number of patients with comorbid conditions like psychiatric and behavioral disorders, which are independent...
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Potential of Gut Microbe-Derived Extracellular Vesicles to Differentiate Inflammatory Bowel Disease Patients from Healthy Controls

Heo M, Park YS, Yoon H, Kim NE, Kim K, Shin CM, Kim N, Lee DH

Background/Aims: This study aimed to evaluate the potential of the stool microbiome and gut microbe-derived extracellular vesicles (EVs) to differentiate between patients with inflammatory bowel disease (IBD) and healthy controls,...
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Improvement of ulcerative colitis control by searching and restricting of inflammatory trigger factors in daily clinical practice

Tsai KY, You JF, Tsai TY, Chern YJ, Hsu YJ, Huang SH, Tsai WS

Background/Aims: Exacerbating factors of ulcerative colitis (UC) are multiple and complex with individual influence. We aimed to evaluate the efficacy of disease control by searching and restricting inflammation trigger factors...
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Compositional changes in fecal microbiota associated with clinical phenotypes and prognosis in Korean patients with inflammatory bowel disease

Shin SY, Kim Y, Kim WS, Moon JM, Lee KM, Jung SA, Park H, Huh EY, Kim BC, Lee SC, Choi CH, on behalf of the IBD Research Group of the Korean Association for the Study of Intestinal Diseases

Background/Aims: The fecal microbiota of Korean patients with inflammatory bowel disease (IBD) was investigated with respect to disease phenotypes and taxonomic biomarkers for diagnosis and prognosis of IBD. Methods: Fecal samples...
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Korean clinical practice guidelines on biologics and small molecules for moderate-to-severe ulcerative colitis

Na SY, Choi CH, Song EM, Bang KB, Park SH, Kim ES, Park JJ, Keum B, Lee CK, Lee BI, Ryoo SB, Koh SJ, Choi M, Kim JS, On behalf of the IBD Research Group of the Korean Association for the Study of Intestinal Diseases

Ulcerative colitis (UC), a relapsing-remitting chronic inflammatory bowel disease (IBD), has a variable natural course but potentially severe disease course. Since the development of anti-tumor necrosis factor (TNF) agents has...
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Factors associated with the prescription of probiotics in patients with inflammatory bowel disease: a cross-sectional study

Kim JK, Cheon JH

Background: Commensal bacteria play an important role in the pathogenesis of inflammatory bowel disease (IBD) and probiotics have been used as treatment options. We aimed to explore the current use...
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Abdominal Pain over 6 Months

Lee SH, Kang SB

Inflammatory bowel disease includes two major types of disease: Crohn’s disease and ulcerative colitis. The incidence of inflammatory bowel disease is increasing worldwide, including in Korea. This chronic disease progresses...
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Microbial Modulation in Inflammatory Bowel Diseases

Yu J, Cheon JH

Gut dysbiosis is one of prominent features in inflammatory bowel diseases (IBDs) which are of an unknown etiology. Although the cause-and-effect relationship between IBD and gut dysbiosis remains to be...
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Context-Dependent Regulation of Type17 Immunity by Microbiota at the Intestinal Barrier

Akuzum B, Lee JY

T-helper-17 (Th17) cells and related IL-17-producing (type17) lymphocytes are abundant at the epithelial barrier. In response to bacterial and fungal infection, the signature cytokines IL-17A/F and IL-22 mediate the antimicrobial...
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Multiple extraintestinal manifestations in a patient with acute severe ulcerative colitis: a case report

Park EY, Baek DH, Hong SM, Song GA

Patients with inflammatory bowel disease (IBD) are at risk for extraintestinal manifestations (EIM) over the course of their disease. As EIMs can involve nearly every organ, and strongly influence the...
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Recent advances in surveillance colonoscopy for dysplasia in inflammatory bowel disease

Na SY, Moon W

Inflammatory bowel disease (IBD) has a global presence with rapidly increasing incidence and prevalence. Patients with IBD including those with ulcerative colitis and Crohn’s disease have a higher risk of...
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Use of Dual-Energy X-ray Absorptiometry in Children with Inflammatory Bowel Disease: A Large Single Centre Study

Jois A, Perera S, Simm P, Alex G

Purpose: Low bone mineral density (BMD) is a complication in children with inflammatory bowel disease (IBD). There are limited data evaluating dual-energy x-ray absorptiometry (DXA) as a screening tool for...
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Comparison between Pediatric Crohn’s Disease and Ulcerative Colitis at Diagnosis in Korea: Results from a Multicenter, Registry-Based, Inception Cohort Study

Park S, Kang B, Kim S, Choi S, Suh HR, Kim ES, Park JH, Kim MJ, Choe YH, Lee YJ, Park JH, Ryoo E, Koh H, Choe BH

Background/Aims: We aimed to compare the differences in pediatric Crohn’s disease (CD) and ulcerative colitis (UC) at diagnosis in Korea. Methods: This was a multicenter, registry-based, inception cohort study conducted at...
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Chemoprevention of Colitis-Associated Dysplasia or Cancer in Inflammatory Bowel Disease

Hsiao SW, Yen HH, Chen YY

The association between inflammatory bowel disease and colorectal cancer is well known. Although the overall incidence of inflammatory bowel disease has declined recently, patients with this disease still have a...
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Treatment with Extracellular Vesicles from Giardia lamblia Alleviates Dextran Sulfate Sodium-Induced Colitis in C57BL/6 Mice

Kim HJ, Lee YJ, Back SO, Cho SH, Lee HI, Lee MR

Inflammatory bowel disease (IBD) is a chronic and recurrent illness of the gastrointestinal tract. Treatment of IBD traditionally involves the use of aminosalicylic acid and steroids, while these drugs has...
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Clinical features of very early-onset inflammatory bowel disease in Japan: a retrospective single-center study

Usami M, Takeuchi I, Kyodo R, Hirano Y, Kashiwagi K, Fujikawa H, Shimizu H, Kawai T, Arai K

Background/Aims: Very early-onset inflammatory bowel disease (VEO-IBD), defined as IBD diagnosed in patients younger than 6 years, is a challenge for pediatric gastroenterologists. Although there have been reports regarding VEO-IBD...
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