Ann Dermatol.  2017 Jun;29(3):337-340. 10.5021/ad.2017.29.3.337.

Interstitial Granulomatous Dermatitis in a Patient with Prostate Cancer

Affiliations
  • 1Department of Dermatology, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea. hazelkimhoho@gmail.com

Abstract

Interstitial granulomatous dermatitis (IGD) is a rare dermatosis, histologically characterized by an interstitial granulomatous infiltrate. It is associated with inflammatory arthritis, various medications, and autoimmune conditions. It is also associated with malignancies such as breast, endometrial, lung, and esophageal cancers as well as hematologic malignancies such as lymphoma and myelodysplastic syndrome. Herein we describe a case of IGD associated with prostate cancer, which has not been reported in the literature.

Keyword

Interstitial granulomatous dermatitis; Prostatic neoplasm

MeSH Terms

Arthritis
Breast
Dermatitis*
Esophageal Neoplasms
Hematologic Neoplasms
Humans
Immunoglobulin D
Lung
Lymphoma
Myelodysplastic Syndromes
Prostate*
Prostatic Neoplasms*
Skin Diseases
Immunoglobulin D

Figure

  • Fig. 1 (A) Multiple, irregularly-shaped, and erythematous to brown patches on the back. (B) Close-up view.

  • Fig. 2 Skin biopsy of the lesion revealing interstitial histiocytic infiltration throughout the dermis with few eosinophils and neutrophils (H&E; A: ×40, B: ×200). (C) Alcian blue at 2.5 pH revealed no mucin deposition in the interstitial infiltrate (×200).


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