Korean J Dermatol.  2016 Aug;54(7):548-551.

A Case of Interstitial Granulomatous Dermatitis

Affiliations
  • 1Department of Dermatology, Gangnam Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea. karenroh@yuhs.ac
  • 2Department of Dermatology, Ajou University School of Medicine, Suwon, Korea.

Abstract

Interstitial granulomatous dermatitis (IGD) is a rare disease that has been associated with multiple systemic diseases, particularly autoimmune conditions like rheumatoid arthritis and systemic lupus erythematosus. IGD has a variable clinical presentation and highly characteristic histological features of interstitial infiltrate of histiocytes between the degenerated collagen bundles. Here we report the case of a 63-year-old woman who presented with a 3-month history of multiple asymptomatic erythematous papules on the bilateral aspects of the trunk. A histopathological examination of the lesion showed an interstitial lymphohistiocytic infiltrate in the dermis. There were also foci of palisading histiocytes along with degenerating collagen bundles.

Keyword

Interstitial granulomatous dermatitis

MeSH Terms

Arthritis, Rheumatoid
Collagen
Dermatitis*
Dermis
Female
Histiocytes
Humans
Immunoglobulin D
Lupus Erythematosus, Systemic
Middle Aged
Rare Diseases
Collagen
Immunoglobulin D
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