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Similar transplant outcomes between haploidentical and unrelated donors after reduced-intensity conditioning with busulfan, fludarabine, and anti-thymocyte globulin in patients with acute leukemia or myelodysplastic syndrome

Choi M, Heo JY, Shin DY, Lee JY, Koh Y, Hong J, Kim I, Yoon SS, Lee JO, Bang SM

BACKGROUND: Although T-cell-replete hematopoietic cell transplantation (HCT) from haploidentical donors (HIDs) using anti-thymocyte globulin (ATG) has shown promising outcomes, previous studies often adopted heterogenous graft sources and conditioning. METHODS: We retrospectively...
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Azathioprine-induced Myelodysplasia Mimicking Myelodysplastic Syndrome

Ohe M

No abstract available.
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Unique Red Blood Cell Morphology Detected in a Patient with Myelodysplastic Syndrome by Three-dimensional Refractive Index Tomography

Koo SE, Jang S, Park CJ, Cho YU, Park Y

The three-dimensional (3-D) shape of erythrocytes is strongly associated with various diseases. However, conventional optical imaging approaches with Wright's staining only provide information on two-dimensional morphology. Here, we employed optical...
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Enhanced polo-like kinase 1 expression in myelodysplastic syndromes

Min KI, Park S, Shin SH, Kwon YR, Kim HJ, Kim YJ

BACKGROUND: Cancer is characterized by uncontrolled cellular proliferation, and Polo-like kinase 1 (PLK1), a key regulator of the cell cycle, is overexpressed in many cancers, including acute leukemia and lymphoma....
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Reclassification of Acute Myeloid Leukemia According to the 2016 WHO Classification

Jung J, Cho BS, Kim HJ, Han E, Jang W, Han K, Lee JW, Chung NG, Cho B, Kim M, Kim Y

We reviewed our leukemia database to reclassify 610 patients previously diagnosed as having acute myeloid leukemia (AML) according to the updated 2016 WHO classification. Nine patients were categorized as having...
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Expression and prognostic significance of microRNAs in Korean patients with myelodysplastic syndrome

Choi Y, Hur EH, Moon JH, Goo BK, Choi DR, Lee JH

BACKGROUND/AIMS: Various alterations of microRNA (miRNA) expression have been reported in myelodysplastic syndrome (MDS). We aimed to investigate the unique patterns and prognostic significance of miRNA expression in Korean patients...
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Red Blood Cell Alloimmunization in Korean Patients With Myelodysplastic Syndrome and Liver Cirrhosis

Kim HY, Cho EJ, Chun S, Kim KH, Cho D

Red blood cell (RBC) alloimmunization varies across human populations and ethnic groups. We evaluated the characteristics of RBC alloimmunization and compared the risk of alloimmunization in Korean patients with myelodysplastic...
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Comparison of High Sensitivity and Conventional Flow Cytometry for Diagnosing Overt Paroxysmal Nocturnal Hemoglobinuria and Detecting Minor Paroxysmal Nocturnal Hemoglobinuria Clones

Park SH, Jeong J, Lee SH, Yoo DW, Choi Y, Jo JC, Lim JH

BACKGROUND: High sensitivity flow cytometry (HS-FCM) was recently developed for diagnosing paroxysmal nocturnal hemoglobinuria (PNH). We compared its performance with conventional flow cytometry (C-FCM) for diagnosing overt PNH and detecting...
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Clinical Effects of Hypomethylating Agents in Patients with Newly Diagnosed Myelodysplastic Syndrome Who Received DNA-Damaging Chemotherapy for Metastatic Breast Cancer

Baek DW, Lee SJ, Sohn SK, Moon JH, Chae YS

The cumulative risk of therapy-related myelodysplastic syndrome (t-MDS) in breast cancer patients exposed to chemotherapy and/or radiotherapy is significantly high compared to that in other cancer patients. This report reviews...
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Differential impact of anti-thymocyte globulin dosing by disease risk index in alternative donor peripheral blood stem cell transplantation in patients with acute leukemia or myelodysplastic syndrome after reduced intensity conditioning

Choi M, Shin DY, Lee JY, Kim I, Yoon SS, Bang SM

No abstract available.
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Long-term response in refractory AML following azacitidine-failed MDS by salvage decitabine-bridged allogenic transplantation

Niscola P, Grazia CD, Mazzone C, Tolu B, de Fabritiis P, Angelucci

No abstract available.
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Transfusion-related acute lung injury in a parturient diagnosed with myelodysplastic syndrome: A case report

Sung TY, Jee YS, Lee SJ, You HJ, Jeong KS, Kang PS

Transfusion-related acute lung injury (TRALI) is defined as a new episode of acute lung injury that occurs during or within 6 hours of a completed transfusion, which is one of...
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Cancer Risk in Patients with Intestinal Behçet’s Disease: A Nationwide Population-Based Study

Han M, Jung YS, Kim WH, Cheon JH, Park S

BACKGROUND/AIMS: The relationship between intestinal Behçet’s disease (BD) and cancer remains unclear. We conducted a nationwide, population-based study to determine the risk of cancer in patients with intestinal BD. METHODS: Using...
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Del(5q) myelodysplastic syndrome combined with pure red cell aplasia

Park J

No abstract available.
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A Case of Pyoderma Gangrenosum with Myelodysplastic Syndrome

Ha JW, Hahm JE, Kim KS, Kim SS, Kim CW

No abstract available.
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Catheter-Related Trichosporon asahii Bloodstream Infection in a Neutropenic Patient with Myelodysplastic Syndrome

Go SE, Lee KJ, Kim Y, Choi JK, Kim YJ, Lee DG

Because primary antifungal prophylaxis is widely used for immunocompromised hosts, the incidences of unusual fungal infections have increased. Trichosporon asahii has emerged as an important life-threatening opportunistic systemic pathogen because...
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Treatment and clinical outcomes of patients relapsing after allogeneic hematopoietic cell transplantation for myelodysplastic syndrome

Choi EJ, Lee JH, Lee JH, Park HS, Ko SH, Seol M, Lee YS, Kang YA, Jeon M, Lee KH

BACKGROUND: Although allogeneic hematopoietic cell transplantation (HCT) is the only curative treatment option for myelodysplastic syndrome (MDS), a substantial number of patients experience relapse. We reviewed the clinical outcomes of...
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Methotrexate-induced myelodysplasia mimicking myelodysplastic syndrome

Kawase Y, Ohe M, Shida H, Horita T, Furuya K, Hashino S

No abstract available.
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No benefit of hypomethylating agents compared to supportive care for higher risk myelodysplastic syndrome

Sohn SK, Moon JH, Lee IH, Ahn JS, Kim HJ, Chung JS, Shin HJ, Park SW, Lee WS, Lee SM, Kim H, Lee HS, Kim YS, Cho YY, Bae SH, Lee JH, Kim SH, Song IC, Kwon JH, Lee YJ

BACKGROUND/AIMS: This study evaluated the role of hypomethylating agents (HMA) compared to best supportive care (BSC) for patients with high or very-high (H/VH) risk myelodysplastic syndrome (MDS) according to the...
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Surgery for Pulmonary Fungal Infections Complicating Hematological Malignancies

Yamamichi , Horio H, Asakawa A, Okui M, Harada M

BACKGROUND: The complication rate of fungal disease is higher among patients with hematological malignancies. We investigated the clinicobacteriological outcomes of resected pulmonary fungal infections complicating hematological malignancies. METHODS: Between 2001 and...
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