Korean J Pediatr Hematol Oncol.  1997 Oct;4(2):370-375.

A Case of Intracranial Granulocytic Sarcoma Associated with Myelodysplastic Syndrome

• Yang EJ
• Lee JS
• Nam SO
• Lim YT

Abstract

Granulocytic sarcoma is an uncommon extramedullary localized tumor composed of granulocytic precursor cells. The majority of cases have been reported in association with acute myeloid leukemia(AML) especially in children, but infrequently may occur in patients with myeloproliferative disorders or myelodysplastic syndromes. Most common sites of involvement were bone, soft tissue, lymph nodes and skin, but gastrointestinal tract, testis, central nervous system are also involved rarely. We present an unusual case of granulocytic sarcoma of the intracranium and the retro-orbital soft tissue occurring in a patient with concurrent myelodysplastic syndrome, diagnosed by brain magnetic resonance images and ultrasound guided needle biopsy.

Keyword

Granulocytic sarcoma; Intracranium; Myelodysplastic syndrome

MeSH Terms

Biopsy, Needle
Brain
Central Nervous System
Child
Gastrointestinal Tract
Granulocyte Precursor Cells
Humans
Lymph Nodes
Myelodysplastic Syndromes*
Myeloproliferative Disorders
Sarcoma, Myeloid*
Skin
Testis
Ultrasonography