Gut Liver.
2015 Nov;9(6):756-760. 10.5009/gnl14338.
Characteristics of Pediatric Inflammatory Bowel Disease in Korea: Comparison with EUROKIDS Data
- Affiliations
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- 1Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea. diksmc.park@samsung.com
- 2Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
- 3Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea.
- 4Department of Internal Medicine, Konyang University School of Medicine, Daejeon, Korea.
- 5Department of Internal Medicine, St. Vincent's Hospital, The Catholic University of Korea College of Medicine, Suwon, Korea.
- KMID: 2377933
- DOI: http://doi.org/10.5009/gnl14338
Abstract
- BACKGROUND/AIMS
Pediatric inflammatory bowel disease (IBD) has been increasing worldwide. The characteristics of pediatric-onset IBD have mainly been reported in Western countries. We investigated the clinical characteristics of pediatric IBD in Korea and compared these with the data from the 5-year European multicenter study of children with new-onset IBD (EUROKIDS registry).
METHODS
Children who were diagnosed with IBD between July 1987 and January 2012 were investigated at five Korean university hospitals. Their clinical characteristics were retrospectively evaluated by medical record review. The results were compared with the EUROKIDS data.
RESULTS
A total of 30 children with Crohn's disease (CD) and 33 children with ulcerative colitis (UC) were enrolled. In comparison with the EUROKIDS group, Korean pediatric IBD patients showed a male predominance (86.7% vs 59.2%, p=0.002 in CD; 75.8% vs 50%, p=0.003 in UC). Korean pediatric CD patients had a higher prevalence of terminal ileal disease (36.7% vs 16.3%, p=0.004) and perianal disease (33.3% vs 8.2%, p<0.001) than patients in the EUROKIDS group. Korean pediatric UC patients had a higher prevalence of proctitis than patients in the EUROKIDS group.
CONCLUSIONS
Our results suggest that the characteristics of Korean pediatric IBD patients and European pediatric IBD patients may be different.
MeSH Terms
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Adolescent
Anus Diseases/complications/epidemiology/pathology
Child
Colitis, Ulcerative/complications/epidemiology/*pathology
Crohn Disease/complications/epidemiology/*pathology
Europe/epidemiology
Female
Humans
Ileal Diseases/complications/epidemiology/pathology
Male
Prevalence
Proctitis/epidemiology/etiology
Registries
Republic of Korea/epidemiology
Retrospective Studies
Sex Factors
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