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Clinical characteristics and nursing diagnoses of pediatric patients hospitalized with inflammatory bowel disease: a single-center retrospective study in South Korea

Jo SY, Bang KS

Purpose: This study aimed to identify clinical characteristics of South Korean pediatric inflammatory bowel disease (IBD) in a children's hospital over the past 5 years, with a specific focus on...
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Infectious complications in patients with inflammatory bowel disease in Asia: the results of a multinational web-based survey in the 8th Asian Organization for Crohn’s and Colitis meeting

Jun YK, Koh SJ, Myung DS, Park SH, Ooi CJ, Sood A, Im JP

Background/Aims: Infectious complications are major concerns when treating patients with inflammatory bowel disease (IBD). This study evaluated clinical differences across countries/regions in the management of infectious diseases in patients with...
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Treatment of inflammatory bowel disease–Asian perspectives: the results of a multinational web-based survey in the 8th Asian Organization for Crohn’s and Colitis meeting

Song EM, Na SY, Hong SN, Ng SC, Hisamatsu T, Ye BD

Background/Aims: As the characteristics of inflammatory bowel disease (IBD) differ between Asians and Westerners, it is necessary to determine adequate therapeutic strategy for Asian IBD patients. We evaluated the current...
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Fecal Fungal Microbiota (Mycobiome) Study as a Potential Tool for Precision Medicine in Inflammatory Bowel Disease

Balderramo DC, Romagnoli PA, Granlund AvB, Catalan-Serra I

There is growing evidence of the role of fungal microbiota in the pathogenesis of inflammatory bowel disease (IBD). Fungi can exert direct pro-inflammatory effects or modify the bacterial composition via...
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Artificial intelligence in inflammatory bowel disease: implications for clinical practice and future directions

Ahmad HA, East JE, Panaccione R, Travis S, Canavan JB, Usiskin K, Byrne MF

Inflammatory bowel disease encompasses Crohn’s disease and ulcerative colitis and is characterized by uncontrolled, relapsing, and remitting course of inflammation in the gastrointestinal tract. Artificial intelligence represents a new era...
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Submucosal fat accumulation in Crohn’s disease: evaluation with sonography

Ripollés T, Martínez-Pérez MJ, Paredes JM, Vizuete J, Martin G, Navarro L

Background/Aims: The study objective is to investigate the ultrasound features that allow suspecting the presence of submucosal fat deposition, called the fat halo sign (FHS), in the intestinal wall of...
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Inflammatory Bowel Disease and Neurodegenerative Diseases

Kim JS, Chen MH, Wang HE, Lu CL, Wang YP, Zhang B

A growing body of evidence has demonstrated an intricate association between inflammatory bowel disease (IBD) and neurodegenerative conditions, expanding beyond previous foci of comorbidities between IBD and mood disorders. These...
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Inflammatory bowel disease (IBD)-disk accurately predicts the daily life burden and parallels disease activity in patients with IBD

Singh A, Gupta YK, Dhaliwal AS, Kahlon BK, Bansal V, Mahajan R, Mehta V, Singh D, Kaur R, Bansal N, Midha V, Sood A

Background/Aims: The inflammatory bowel disease (IBD)-disk is a validated, visual, 10-item, self-administered questionnaire used to evaluate IBD-related disability. The present study aimed to evaluate IBD-disk in assessment of IBD daily...
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Pregnancy Outcomes Associated With Biologic Agent Exposure in Patients With Several Rheumatic Diseases and Inflammatory Bowel Diseases

Ahn SM, Joo YB, Kim YJ, Bang SY, Lee HS

Background: This study aimed to analyze pregnancy outcomes based on biologic agents use in women using the nationwide population-based database. Methods: The study used the claims database to identify women of...
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Cellular and Molecular Mechanisms of Intestinal Fibrosis

Wu X, Lin X, Tan J, Liu Z, He J, Hu F, Wang, Y, Chen M, Liu F, Mao R

Intestinal fibrosis associated stricture is a common complication of inflammatory bowel disease usually requiring endoscopic or surgical intervention. Effective anti-fibrotic agents aiming to control or reverse intestinal fibrosis are still...
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Brain–Gut–Microbiota Axis

Lee A, Lee JY, Jung SW, Shin SY, Ryu HS, Jang SH, Kwon JG, Kim YS

Patients frequently report that stress causes or exacerbates gastrointestinal (GI) symptoms, indicating a functional relationship between the brain and the GI tract. The brain and GI tract are closely related...
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Concomitant ankylosing spondylitis can increase the risk of biologics or small molecule therapies to control inflammatory bowel disease

Jun YK, Yoon H, Koh SJ, Kim AH, Kim KW, Park JW, Lee HJ, Kang HW, Im JP, Park YS, Kim JS, on behalf of Seoul National University Inflammatory Bowel Disease Research Network (SIRN)

Background/Aims: Patients with inflammatory bowel disease (IBD) are diagnosed with ankylosing spondylitis (AS) often. However, the disease course of patients with both IBD and AS is not well understood. This...
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Clinical spectrum of elderly-onset inflammatory bowel disease in India

Gupta YK, Singh A, Narang V, Midha V, Mahajan R, Mehta V, Singh D, Bansal N, Durairaj MVB, Dutta AK, Sood A

Background/Aims: Inflammatory bowel disease (IBD) is increasingly being recognized in elderly patients. Data on clinical spectrum of elderly-onset IBD patients is lacking from India. Methods: A cross-sectional retrospective analysis of a...
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De-escalation of Therapy in Patients with Quiescent Inflammatory Bowel Disease

Miyatani Y, Kobayashi T

Inflammatory bowel disease is a chronic disease of unknown origin that requires long-term treatment. The optical duration of maintenance treatment once remission has been achieved remains unclear. When discussing a...
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Bone Mineral Density in Patients with Pediatric Inflammatory Bowel Disease Using Dual Energy X-Ray Absorptiometry

Isa HM, Ezzaldin AA, Alabbasi MM, ALaazmi NH, Masood AS, Alabbasi HM

Background: Inflammatory bowel disease (IBD) is a chronic inflammatory immune-mediated condition that affects the gastrointestinal system and alters bone growth and bone mineral density (BMD). Here we aimed to study...
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Potential of Gut Microbe-Derived Extracellular Vesicles to Differentiate Inflammatory Bowel Disease Patients from Healthy Controls

Heo M, Park YS, Yoon H, Kim NE, Kim K, Shin CM, Kim N, Lee DH

Background/Aims: This study aimed to evaluate the potential of the stool microbiome and gut microbe-derived extracellular vesicles (EVs) to differentiate between patients with inflammatory bowel disease (IBD) and healthy controls,...
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Factors associated with the prescription of probiotics in patients with inflammatory bowel disease: a cross-sectional study

Kim JK, Cheon JH

Background: Commensal bacteria play an important role in the pathogenesis of inflammatory bowel disease (IBD) and probiotics have been used as treatment options. We aimed to explore the current use...
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Abdominal Pain over 6 Months

Lee SH, Kang SB

Inflammatory bowel disease includes two major types of disease: Crohn’s disease and ulcerative colitis. The incidence of inflammatory bowel disease is increasing worldwide, including in Korea. This chronic disease progresses...
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Microbial Modulation in Inflammatory Bowel Diseases

Yu J, Cheon JH

Gut dysbiosis is one of prominent features in inflammatory bowel diseases (IBDs) which are of an unknown etiology. Although the cause-and-effect relationship between IBD and gut dysbiosis remains to be...
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Context-Dependent Regulation of Type17 Immunity by Microbiota at the Intestinal Barrier

Akuzum B, Lee JY

T-helper-17 (Th17) cells and related IL-17-producing (type17) lymphocytes are abundant at the epithelial barrier. In response to bacterial and fungal infection, the signature cytokines IL-17A/F and IL-22 mediate the antimicrobial...
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