Korean J Fam Med.  2017 Mar;38(2):99-101. 10.4082/kjfm.2017.38.2.99.

Confusion, Faciobrachial Dystonic Seizures, and Critical Hyponatremia in a Patient with Voltage-Gated Potassium Channel Encephalitis

Affiliations
  • 1Department of Internal Medicine, Redcliffe Hospital, Redcliffe, Queensland, Australia. julianyaxley@yahoo.com.au

Abstract

Autoimmune limbic encephalitis is a rare cause of encephalitic disease. It is associated with various target antigens and is difficult to diagnose, and experience with its treatment is limited. This case report describes a 69-year-old man, who presented with life-threatening hyponatremia and confusion, following several months of gradually worsening faciobrachial dystonic seizures. Faciobrachial dystonic seizures are a well-described feature classically observed in voltage-gated potassium channel autoimmune encephalitis. The presence of chronic hyponatremia without cognitive dysfunction, eventually culminating in an acute episode of encephalopathy and severe hyponatremia, is a pattern of natural history not previously documented in this condition.

Keyword

Seizure; Dystonia; Encephalitis; Hyponatremia

MeSH Terms

Aged
Brain Diseases
Dystonia
Encephalitis*
Humans
Hyponatremia*
Limbic Encephalitis
Natural History
Potassium Channels, Voltage-Gated*
Seizures*
Potassium Channels, Voltage-Gated
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