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A Case of Voltage Gated Potassium Channel Antibodies-associated Nonparaneoplastic Limbic Encephalitis

Won Y, Kim JY, Park HJ, Park S, Lee JD, Choi IS

  • KMID: 1572313
  • J Korean Neurol Assoc.
  • 2006 Apr;24(2):148-152.
Limbic encephalitis has been reported usually as an autoimmune complication related to onconeuronal antigen of underlying cancer with poor prognosis. Antibodies reactive with neuronal voltage-gated potassium channels (VGKCs) are recently...
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Confusion, Faciobrachial Dystonic Seizures, and Critical Hyponatremia in a Patient with Voltage-Gated Potassium Channel Encephalitis

Yaxley J

Autoimmune limbic encephalitis is a rare cause of encephalitic disease. It is associated with various target antigens and is difficult to diagnose, and experience with its treatment is limited. This...
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Leucine-rich, Glioma Inactivated 1 Antibody-related Limbic Encephalitis Presenting as Recurrent Complex Partial Seizures

Kim TE, Kim S, Park DS, Lee ST, Sung KB, Park SA

No abstract available.
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Myasthenia in Acquired Neuromyotonia

Byun JI, Moon HJ, Hong YH

  • KMID: 2400179
  • J Clin Neurol.
  • 2014 Jan;10(1):69-71.
BACKGROUND: Acquired neuromyotonia (NMT) forms part of the spectrum of acquired peripheral nerve hyperexcitability syndrome, and is thought to be caused by antibodies to voltage-gated potassium channels (VGKC). Exertional weakness...
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Steroid Responsive Recurrent Limbic Encephalitis Associated With LGI1 Antibodies

Noh KH, Kim SJ, Cho JW, Shin JH, Lee JH

  • KMID: 2191160
  • J Korean Neurol Assoc.
  • 2014 May;32(2):91-94.
Limbic encephalitis (LE) is characterized by short-term memory loss, disorientation, agitation, seizures, and histological evidence of mesial temporal lobe inflammation. Leucine-rich, glioma inactivated 1 (LGI1) is the autoantigen associated with...
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Anti-LGI1 Antibody Autoimmune Encephalitis Which Manifests Faciobrachial Dystonic Seizure

Kim H, Kim B, Hwang J, Lee Y, Lee ST, Kang JK

  • KMID: 1708059
  • J Korean Neurol Assoc.
  • 2014 Feb;32(1):22-25.
Anti-LGI1 (leucine-rich glioma inactivated-1) antibody encephalitis is one of autoimmune encephalitis. We report a 66-year-old man who presented with frequent, brief dystonic seizures which involve predominantly ipsilateral face and arm...
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Change of voltage-gated potassium channel 1.7 expressions in monocrotaline-induced pulmonary arterial hypertension rat model

Lee H, Kim KC, Hong YM

PURPOSE: Abnormal potassium channels expression affects vessel function, including vascular tone and proliferation rate. Diverse potassium channels, including voltage-gated potassium (Kv) channels, are involved in pathological changes of pulmonary arterial...
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Inhibition by Norfluoxetine, the Major Metabolite of Fluoxetine, of Voltage-Gated K+ Channels in Primary Cultured Rat Hippocampal Neurons

Han TH, Choi JS, Kwak IS, Choi YJ, Kim MJ, Min DS, Rhie DJ, Yoon SH, Jo YH, Kim MS, Hahn SJ

BACKGROUND: Fluoxetine (Prozac), a selective serotonin reuptake inhibitor, has been shown to be effective in the treatment of depression. We investigated the effects of norfluoxetine, the major active metabolite of...
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Serotonin contracts the rat mesenteric artery by inhibiting 4-aminopyridine-sensitive Kv channels via the 5-HT2A receptor and Src tyrosine kinase

Sung DJ, Noh HJ, Kim JG, Park SW, Kim B, Cho H, Bae YM

  • KMID: 2154286
  • Exp Mol Med.
  • 2013 Dec;45(12):e67.
Serotonin (5-hydroxytryptamine (5-HT)) is a neurotransmitter that regulates a variety of functions in the nervous, gastrointestinal and cardiovascular systems. Despite such importance, 5-HT signaling pathways are not entirely clear. We...
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Mechanism of L-NAME-resistant endothelium-dependent relaxation induced by acetylcholine in rabbit renal artery

Yeon DS, Ahn DS, Lee YH, Kwon SC

  • KMID: 1581025
  • Korean J Physiol Pharmacol.
  • 2000 Dec;4(6):471-477.
In the rabbit renal artery, acetylcholine (ACh, 1 nM ~ 10 micrometer) induced endothelium-dependent relaxation of arterial rings precontracted with norepinephrine (NE, 1 micrometer) in a dose-dependent manner. NG-nitro-L-arginine (L-NAME, 0.1 mM), an...
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Testosterone Causes Simultaneous Decrease of [Ca2+]i and Tension in Rabbit Coronary Arteries: by Opening Voltage Dependent Potassium Channels

Won EK, Won JE, Kwon SC, Lee YH, Nam TS, Ahn DS

The relationship between the level of testosterone and the incidence of coronary heart disease is still controversial in the view of the results of clinical and epidemiologic studies. This uncertainty...
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Expression of the IKr components KCNH2 (rERG) and KCNE2 (rMiRP1) during late rat heart development

Chun KR, Koenen M, Katus HA, Zehelein J

  • KMID: 1094081
  • Exp Mol Med.
  • 2004 Aug;36(4):367-371.
To understand molecular mechanisms that regulate formation and maintenance of cardiac IKr (rapidly activating component of the delayed rectifier K+ current), we have investigated the spatiotemporal expression pattern of two...
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Heterogeneous Composition of Voltage-Dependent K+ Currents in Hepatic Stellate Cells

Lee DH, Kimm K, Kim HL, Han BG

PURPOSE: Hepatic stellate cells (HSC) are a type of pericyte with varying characteristics according to their location. However, the electrophysiological properties of HSC are not completely understood. Therefore, this study...
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Characteristics of Potassium and Calcium Currents of Hepatic Stellate Cells (Ito) in Rat

Lee KI, Kong ID, Baik SK, Kim HS, Lee DK, Kwon SO, Chun BG

Hepatic stellate cells (HSCs) are known to play a role in the pathogenesis of the increased intrahepatic vascular resistance found in chronic liver diseases. The aim of this study was...
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