J Korean Neurol Assoc.
2006 Apr;24(2):148-152.
A Case of Voltage Gated Potassium Channel Antibodies-associated Nonparaneoplastic Limbic Encephalitis
- Affiliations
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- 1Department of Neurology, Yonsei University College of Medicine, Seoul, Korea. scpark@yumc.yonsei.ac.kr
- 2Department of Nuclear Medicine, Yonsei University College of Medicine, Seoul, Korea.
Abstract
- Limbic encephalitis has been reported usually as an autoimmune complication related to onconeuronal antigen of underlying cancer with poor prognosis. Antibodies reactive with neuronal voltage-gated potassium channels (VGKCs) are recently recognized as a pathogenic cause in nonparaneoplastic limbic encephalitis, which is responsive to immunotherapy. We report a patient who had subacute encephalopathy with clinical and radiographic evidences of limbic encephalitis. The patient was seropositive for VGKC antibodies and resulted in a good prognosis with steroids. This has not yet been reported in Korea.
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