Dement Neurocogn Disord.  2014 Sep;13(3):79-82. 10.12779/dnd.2014.13.3.79.

Non-paraneoplastic Autoantibody-negative Limbic Encephalitis Characterized by Mild Memory Impairment: A Case Report

Affiliations
  • 1Department of Neurology, VHS Medical Center, Seoul, Korea. astro76@naver.com

Abstract

Encephalitis that primarily involves limbic system structures such as the hippocampus and parahippocampal gyrus has been described in early papers, most commonly characterized by a subacute progressive impairment of short-term memory, psychiatric features and seizures. While these findings might be caused by viral infections or systemic autoimmune disorders, many patients with limbic encephalitis have an immune-mediated etiology (paraneoplastic or not) characterized with serum or CSF antineuronal antibodies. This case reports about non-paraneoplastic autoantibody-negative limbic encephalitis in which there are no detection of antigens and no evidence of tumors.

Keyword

Limbic encephalitis; Memory impairment; Non-paraneoplastic; Autoantibody negative

MeSH Terms

Antibodies
Encephalitis
Hippocampus
Humans
Limbic Encephalitis*
Limbic System
Memory*
Memory, Short-Term
Parahippocampal Gyrus
Seizures
Antibodies
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