Korean J Endocr Surg.
2008 Sep;8(3):210-214. 10.16956/kjes.2008.8.3.210.
Anaplastic Transformation of Metastatic Papillary Thyroid Carcinomas in the Cervical Lymph Nodes: Report of 3 Cases
- Affiliations
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- 1Department of Surgery, Yonsei University College of Medicine, Seoul, Korea. cspark1@yuhs.ac
- 2Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
- KMID: 2375856
- DOI: http://doi.org/10.16956/kjes.2008.8.3.210
Abstract
- Anaplastic thyroid carcinoma (ATC) is a rare disease that shows very aggressive behavior. Most ATCs arise from pre-existing thyroid carcinomas. However, anaplastic transformation occurring in metastatic cervical nodes is extremely rare. We report herein on 3 cases of anaplastic transformation of metastatic lateral cervical lymph nodes from primary papillary thyroid carcinoma (PTC), which happened long after the initial surgical treatment. All the patients died of disease within 4 months in spite of aggressive treatment for the lesions. Our experience supports that appropriate lymph node dissection is mandatory at the time of initial surgery even for differentiated thyroid carcinomas.
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Cited by 1 articles
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Coexistent Papillary Thyroid Carcinoma and Its Anaplastic Transformation in Cervical Lymph Node Metastasis
Seulki Song, Dong-Han Lee, Hyojin Kim, Woo-Jin Jeong
Int J Thyroidol. 2020;13(1):55-59. doi: 10.11106/ijt.2020.13.1.55.
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