Ann Lab Med.  2016 Nov;36(6):611-613. 10.3343/alm.2016.36.6.611.

A Novel Integron Gene Cassette Harboring VIM-38 Metallo-β-lactamase in a Clinical Pseudomonas aeruginosa Isolate

Affiliations
  • 1Department of Biology, Faculty of Arts & Sciences, Recep Tayyip ErdoÄŸan University, Rize, Turkey. cemal.sandalli@erdogan.edu.tr
  • 2Department of Genetics and Bioengineering, Faculty of Engineering and Natural Sciences, Gümüşhane University, Gümüşhane, Turkey.
  • 3Department of Medical Microbiology, Faculty of Medicine, GaziosmanpaÅŸa University, Tokat, Turkey.
  • 4Department of Medical Microbiology, Faculty of Medicine, Recep Tayyip Erdogan University, Rize, Turkey.

Abstract

No abstract available.


MeSH Terms

Anti-Bacterial Agents/pharmacology
DNA, Bacterial/chemistry/genetics/metabolism
Drug Resistance, Bacterial
Integrons/*genetics
Microbial Sensitivity Tests
Pseudomonas aeruginosa/drug effects/*enzymology/isolation & purification
Sequence Analysis, DNA
beta-Lactamases/*genetics
Anti-Bacterial Agents
DNA, Bacterial
beta-Lactamases

Figure

  • Fig. 1 Structure of the blaVIM-38-carrying class 1 integron gene cassette in Pseudomonas aeruginosa.Abbreviations: Pint, integrase promoter; Pant, promoter of inserted gene(s); intI1, class 1 integrase; attI1, integron-associated recombination site; qacEΔ1, quaternary ammonium compound resistance gene cassette; ™, sulfonamide resistance gene; blaVIM-38, Verona Integron-Encoded Metallo-β-lactamase 38; CS, conserved segment.


Reference

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