Ann Lab Med.  2016 Jul;36(4):380-383. 10.3343/alm.2016.36.4.380.

First Case of Diffuse Large B-Cell Lymphoma Subtype of Monomorphic Post-Transplant Lymphoproliferative Disorder With 3q27 Translocation

• Kim H
• Kim IS
• Lee EY
• Shin DH
• Cho SH

• KMID: 2373562
• DOI: http://doi.org/10.3343/alm.2016.36.4.380

Abstract

No abstract available.

MeSH Terms

Bone Marrow/pathology
Chromosomes, Human, Pair 3
Chromosomes, Human, Pair 6
Female
Humans
In Situ Hybridization, Fluorescence
Karyotyping
Lymphoma, Large B-Cell, Diffuse/*diagnosis/genetics
Middle Aged
Proto-Oncogene Proteins c-bcl-6/genetics
Tomography, X-Ray Computed
Translocation, Genetic
Proto-Oncogene Proteins c-bcl-6

Figure

• 

  Fig. 1 Histopathologic findings of a monomorphic post-transplant lymphoproliferative disorder, diffuse large B-cell lymphoma subtype involving spleen (A, B, and C) and bone marrow (D, E, and F). (A) Hematoxylin and Eosin stain, ×40. (B) CD20 stain, ×40. (C) CD3 stain, ×40. (D) Hematoxylin and Eosin stain, ×100. (E) CD20 stain, ×100. (F) CD3 stain, ×100.

• 

  Fig. 2 Karyotype analysis of bone marrow specimen showing t(3;6)(q27;p22) and del(14)(q31) (A) and FISH results showing BCL6 (3q27) rearrangement and loss of IGH (14q32) signals using dual-color, and break-apart probes, respectively (B and C).

Reference

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