J Korean Gastric Cancer Assoc.  2004 Dec;4(4):282-285.

A Case of Advanced Gastric Cancer with Virchow's Node and Lung Metastasis Successfully Resected after Combined Chemotherapy of Taxotere, CDDP, and 5-FU

Affiliations
  • 1Korea Gastric Cancer Center, Korea. oltx62@hotmail.com
  • 2Department of Oncology, Seoul Paik Hospital, College of Medicine, Inje University, Seoul, Korea.
  • 3Department of Pathology, Seoul Paik Hospital, College of Medicine, Inje University, Seoul, Korea.

Abstract

We report a case of advanced gastric cancer with Virchow's node and lung metastasis that responded remarkably to preoperative chemotherapy. A 47-year-old female patient was diagnosed as having incurable advanced gastric cancer with Virchow's node and multiple lung metastasis. Preoperative chemotherapy with Taxotere, CDDP and 5FU was carried out. After four courses of the regimen, the Virchow's node and the lung metastasis had disappeared, and a marked reduction of the gastric lesion was observed on the CT scan. Consequently, the patient underwent a total gastrectomy with D2 lymph node dissection. On histopathological examination, cancer cells were found to have infiltrated up to the muscle layer of the gastric wall, and 42 out of 60 resected lymph nodes were found to be metastatic. The patient received another two courses of chemotherapy after the operation

Keyword

Gastric cancer; Lung metastasis; Preoperative chemotherapy

MeSH Terms

Drug Therapy*
Female
Fluorouracil*
Gastrectomy
Humans
Lung*
Lymph Node Excision
Lymph Nodes
Middle Aged
Neoplasm Metastasis*
Stomach Neoplasms*
Tomography, X-Ray Computed
Fluorouracil
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