J Korean Ophthalmol Soc.  2017 Mar;58(3):367-371. 10.3341/jkos.2017.58.3.367.

A Case Report of Occipital Lobe Epilepsy and Related Optical Coherence Tomography Findings

Affiliations
  • 1Department of Ophthalmology, Myongji Hospita, Seonam University College of Medicine, Goyang, Korea. skdh17@hanmail.net
  • 2Department of Neurology, Myongji Hospital, Seonam University College of Medicine, Goyang, Korea.

Abstract

PURPOSE
In the present case report, visual pathway damage confirmed by retinal ganglion cell layer (GCL) damage on optical coherence tomography (OCT) in occipital lobe epilepsy was described.
CASE SUMMARY
A 25-year-old female with idiopathic generalized epilepsy developed visual blurring followed by a generalized seizure. On brain magnetic resonance imaging (MRI), very subtle changes of the cortex in the left parietooccipital lobe were observed. Two days after the attack, even after the disappearance of epileptiform wave on electroencephalogram (EEG), visual acuity in both eyes was 0.5 and a perimetry revealed nearly complete visual defect in both eyes. OCT showed severe thinning of GCL and mild thinning of retinal nerve fiber layer (RNFL). No additional seizure attack occurred thereafter. One month after the attack, her visual acuity was recovered to 1.0 in both eyes and her left visual hemifield defect was recovered. However, even 6 months after the attack, her right visual hemifield defect and GCL damage persisted in both eyes.
CONCLUSIONS
We reported a case in which the visual pathway damage caused by occipital lobe epilepsy was identified using OCT, despite very subtle changes in brain imaging. This case indicated GCL thinning is an objective and prognostic index for the irreversible visual field defect in occipital lobe epilepsy.

Keyword

Ganglion cell layer; Occipital lobe epilepsy; Optical coherence tomography; Visual seizure; Visual field defect

MeSH Terms

Adult
Brain
Electroencephalography
Epilepsies, Partial*
Epilepsy, Generalized
Female
Humans
Magnetic Resonance Imaging
Nerve Fibers
Neuroimaging
Occipital Lobe*
Retinal Ganglion Cells
Retinaldehyde
Seizures
Tomography, Optical Coherence*
Visual Acuity
Visual Field Tests
Visual Fields
Visual Pathways
Retinaldehyde
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