- NF-kappa B activation following optic nerve transection
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Choi JS, Kim-Yoon S, Joo CK
- KMID: 1375105
- Korean J Ophthalmol.
- 1998 Jun;12(1):19-24.
- doi: 10.3341/kjo.1998.12.1.19
In order to elucidate in vivo neuronal cell death in the retina, and involvement of NF-kappa B in this process, we studied the degeneration of retinal ganglion cells (RGCs) and... -
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- The Changes of the Retinal Ganglional Cells in the Pressure-induced Ischemic Rabbit Retina
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Park TK, Son WS, Kwak HW
- KMID: 2337000
- J Korean Ophthalmol Soc.
- 2001 May;42(5):772-782.
PURPOSE: There were many studies on the distributions of the retinal ganglion cells(RGC) in the experimental model of the retinal ischemia. RGC was known to be more sensitive to the... -
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- Effect of Creatine on the Survival of RGC-5 Cells under Serum Deprivation
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Kim JW, Hong JH, Kang SH, Kim YY
- KMID: 2214583
- J Korean Ophthalmol Soc.
- 2011 May;52(5):618-623.
- doi: 10.3341/jkos.2011.52.5.618
PURPOSE: To evaluate the protective effect of creatine on the survival of retinal ganglion cells after serum deprivation. METHODS: RGC-5 cells were exposed to 5 mM creatine with serum-free media for... -
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- Pilocarpine Induced Expression of Nitric Oxide Synthase in R18A5 Retinal Ganglion Cell Line
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Choi KD, Bae JH, Huh K, Chung JH
- KMID: 2336932
- J Korean Ophthalmol Soc.
- 2000 Jul;41(7):1466-1472.
Pilocarpine is a direct cholinergic agonist and reduces intraocular pressure by enhancing aqueous outflow. A recent study reveals that pilocarpine induces apoptotic cell death in retinal ganglion cells; activation of... -
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- Mechanism of Tissue Injury in Experimental Retinal Artery Occlusion: Morphological Study I
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Park SJ, Kang SG, Choi YI
- KMID: 2124625
- J Korean Ophthalmol Soc.
- 2000 Nov;41(11):2450-2457.
We used an animal model of laser-induced retinal artery occlusion to study the temporal and spatial patterns of tissue injury and to identify apoptosis-like morphologic changes.We performed fundus exam and... -
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- Expression of Nitric Oxide Synthase Isoforms in a Rat Model of Chronic Glaucoma
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Kim YH, Park CK
- KMID: 2337407
- J Korean Ophthalmol Soc.
- 2006 Jun;47(6):977-985.
PURPOSE: This study investigated the expression of three isoforms of nitric oxide synthase (NOS): neuronal (nNOS), inducible (iNOS), and endothelial (eNOS) in an experimental rat model of chronic glaucoma. The... -
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- Apoptosis of Retinal Ganglion Cell after Ischemia-reperfusion Injury of Optic Nerve in Rabbits
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Park KH, Kim DM
- KMID: 2205402
- J Korean Ophthalmol Soc.
- 1998 Nov;39(11):2687-2700.
To develop a new animal model for ischemia-reperfusion infury of the optic nerve in rabbits and to investigate the pattern of retinal ganglion cell apoptosis and bcl-2 staining in the... -
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- Functional Analysis and Immunochemical Analyses of Ca²⺠Homeostasis-Related Proteins Expression of Glaucoma-Induced Retinal Degeneration in Rats
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Lee JY, Oh SJ
- KMID: 2405305
- Exp Neurobiol.
- 2018 Feb;27(1):16-27.
- doi: 10.5607/en.2018.27.1.16
The retinal degeneration resulting from elevated intraocular pressure was evaluated through functional and morphological analyses, for better understanding of the pathophysiology of glaucoma. Ocular hypertension was induced via unilateral episcleral... -
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- Characteristics of Light-evoked Retinal Ganglion Cell Activity with Postnatal Maturation in SD Rat
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Ye JH, Goo YS
- KMID: 1590883
- Korean J Med Phys.
- 2005 Dec;16(4):214-219.
As part of Korean retinal prosthesis project, we have provided preliminary experimental results regarding voltage parameters for the stimulation of chemically degenerated rabbit retina. Since our APB-treated chemically degenerated retina... -
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- Apoptotic Cell Death in Experimental Retinal Vein Occlusion
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Kang SG, Chung H
- KMID: 2336899
- J Korean Ophthalmol Soc.
- 2000 Mar;41(3):576-584.
We used an animal model of laser-induced retinal vein occlusion to study the temporal and spatial patterns of neuronal necrosis and apoptosis. After photodynamic retinal vein thrombosis with argon-green laser,... -
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- Expression of Glutamate Receptors in Experimental Rat Model of Chronic Glaucoma
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Kim JH, Park CK
- KMID: 2208401
- J Korean Ophthalmol Soc.
- 2006 Mar;47(3):468-476.
PURPOSE: To investigate the changes of glutamate receptor expressions in the retina of the chronic ocular hypertension model of chronic glaucoma. METHODS: We performed quantification and localization of glutamate receptors... -
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- Effect of High Glucose on the Production of Reactive Oxygen Species in R28 Cells
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Lee JM, Kim JW
- KMID: 2425092
- J Korean Ophthalmol Soc.
- 2010 May;51(5):746-750.
PURPOSE: To investigate the effect of high glucose (HG) on the production of reactive oxygen species (ROS) in retinal precursor R28 cells. METHODS: R28 cells were incubated with low glucose (5... -
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- Comparison of Retinal Waveform between Normal and rd/rd Mouse
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Ye JH, Seo JH, Goo YS
- KMID: 1482431
- Korean J Med Phys.
- 2008 Sep;19(3):157-163.
Retinal prosthesis is regarded as the most feasible method for the blind caused by retinal diseases such as retinitis pigmentosa or age-related macular degeneration. One of the prerequisites for the... -
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- Effect of Heat Shock Protein 72 Expression on Etoposide-induced Cell Death of Rat Retinal Ganglion Cells
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Sohn S, Im JE, Kim TE, Kee C
- KMID: 1501796
- Korean J Ophthalmol.
- 2013 Feb;27(1):48-51.
- doi: 10.3341/kjo.2013.27.1.48
PURPOSE: To assess whether the expression of heat shock protein 72 (Hsp72) protects rat retinal ganglion cells (RGC-5) from apoptotic cell death. METHODS: Hsp72 expression in RGC-5 cells transduced with replication-deficient... -
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- Expression of the Na(+)-K(+)-2Cl(-)-Cotransporter 2 in the Normal and Pressure-Induced Ischemic Rat Retina
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Kim DH, Ahn MD
- KMID: 1376127
- Korean J Ophthalmol.
- 2012 Jun;26(3):203-211.
- doi: 10.3341/kjo.2012.26.3.203
PURPOSE: To evaluate the expression of the Na(+)-K(+)-2Cl(-)-cotransporter 2 (NKCC2) in the ischemic rat retina. METHODS: Retinal ischemia was induced by pressures 90 to 120 mmHg, above systemic systolic pressure. Immunohistochemistry... -
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- Comparison of Retinal Ganglion Cell Damage in Glaucoma and Retinal Vein Occlusion by Visual Field
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Lee J, Jeon S, Park HY
- KMID: 2445139
- J Korean Ophthalmol Soc.
- 2019 May;60(5):455-462.
- doi: 10.3341/jkos.2019.60.5.455
PURPOSE: We analyzed and compared retinal ganglion cell damage between patients with glaucoma and those with branched retinal vein occlusion (BRVO). We performed two types of visual field examinations. METHODS: We... -
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- Waveform Sorting of Rabbit Retinal Ganglion Cell Activity Recorded with Multielectrode Array
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Jin GH, Lee TS, Goo YS
- KMID: 2080301
- Korean J Med Phys.
- 2005 Sep;16(3):148-154.
Since the output of retina for visual stimulus is carried by neurons of very diverse functional properties, it is not adequate to use conventional single electrode for recording the retinal... -
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- Experimental Retianl Vein Occlusion in Albino Rats
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Ham DI, Kim SJ, Park SJ, Chang K, Chung H
- KMID: 2124087
- J Korean Ophthalmol Soc.
- 1998 Mar;39(3):530-538.
The retinal vein occlusion is one of the most common, vision-threatening retinal diseases, and the establishment of animal model in rats will be of great help for further study. We... -
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- Functional Connectivity Map of Retinal Ganglion Cells for Retinal Prosthesis
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Ye JH, Ryu SB, Kim KH, Goo YS
- KMID: 2285357
- Korean J Physiol Pharmacol.
- 2008 Dec;12(6):307-314.
- doi: 10.4196/kjpp.2008.12.6.307
Retinal prostheses are being developed to restore vision for the blind with retinal diseases such as retinitis pigmentosa (RP) or age-related macular degeneration (AMD). Among the many issues for prosthesis... -
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- Iron-induced cytotoxicity in cultured rat retinal neurons
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Sohn J, Yoon YH
- KMID: 1043979
- Korean J Ophthalmol.
- 1998 Dec;12(2):77-84.
- doi: 10.3341/kjo.1998.12.2.77
Oxidative stress has been proposed as a major injury mechanism in the central nervous system including the retina. In this study, as an initial attempt to study the mechanism of... -
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