Exp Neurobiol.
2017 Feb;26(1):66-69. 10.5607/en.2017.26.1.66.
Relapsing Polychondritis Presented with Encephalitis Followed by Brain Atrophy
- Affiliations
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- 1Department of Neurology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul 06974, Korea. icandr@hanmail.net
- 2Department of Neurology, Inha University Hospital, Inha University College of Medicine, Incheon 22332, Korea.
- 3Department of Pathology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul 06974, Korea.
- 4Department of Rheumatology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul 06974, Korea.
- KMID: 2368656
- DOI: http://doi.org/10.5607/en.2017.26.1.66
Abstract
- Relapsing polychondritis (RP) is a rare autoimmune disease that is characterized by inflammatory reaction of unknown etiology and destruction of cartilaginous structures. Characteristic symptoms of this disease include cartilage inflammation of the ear, nose, larynx, trachea, bronchi, joints, eyes, heart and skin. Concomitance with neurologic symptom is very rare in RP, and the detailed underlying mechanism of neurological involvement associated with RP is not fully understood. We herein described an unusual recurrent case of inflammatory brain lesions associated with RP, with attention to clinical manifestations, autoimmune disease involvement, and therapeutic effects.
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