Allergy.
1995 Jun;15(2):268-274.
A Case of Baker's Asthma
Abstract
- Baker's asthma is a common allergic occupational lung disease caused by exposure to wheat flour in bakeries. We experienced a case of occupational asthma induced by wheat flour in a baker. A 22-year-old male patient who had baked for 3 years, had suffered from rhinorrhea, sneezing, paroxysmal coughing and dyspnea for 2 years expecially after handling wheat flour. Serum total IgE level by PRIST was 1, 571 IU/ml. Allergy skin prick test demonstrated a positive response on cat fur. 3x3/20x 15, house dust, 4 x 4/25 x 23, Dermatophagoides(D) fari-nae, 4 x 3/25 x 24, D. pteronyssinus, 5 x 4/35 x 25(ram). IgE-RAST revealed class 3 to cat fur. class 4 to D. farinae, class 4 to D. pteronyssinus, class 1 to Tyrophagus putrescen tiae, class 0 to wheat grain respectively. Allergy skin prick test and intradermal test with home made wheat flour extracts (1:4w/v) which came from the patient's bakery result in a positive response. 2 x 2/7 x 4, 15 x 14/43 x 30(mm) respectively. The bronchoprovocation test with home made wheat flour extracts (finally 1: 10 w/v) showed a significant bronchoconstriction with 41% of FEVi fall after 10 minutes of the inhalation. D. farinae-bronchoprovocation test demonstrated a dual asthmatic response. The patient was recommended to change his work-site with anti-asthmatic medication and cessation of exposure result in marked improvement in his asthmatic symptoms.
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